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  1. Mixed microbial infections of the respiratory tracts with P. aeruginosa and A. fumigatus capable of producing biofilms are commonly found in cystic fibrosis patients. The primary objective of this study was to de...

    Authors: Elias K Manavathu, Dora L Vager and Jose A Vazquez
    Citation: BMC Microbiology 2014 14:53
    Content type: Research article Published on:

  2. Meyerozyma guilliermondii (anamorph Candida guilliermondii) and Meyerozyma caribbica (anamorph Candida fermentati) are closely related species of the genetically heterogenous M. guilliermondii complex. Conventio...

    Authors: Wahengbam Romi, Santosh Keisam, Giasuddin Ahmed and Kumaraswamy Jeyaram
    Citation: BMC Microbiology 2014 14:52
    Content type: Methodology article Published on:

  3. Extensive use of antibiotics has fostered the emergence of superbugs that are resistant to multidrugs, which becomes a great healthcare and public concern. Previous studies showed that quorum sensing signal DS...

    Authors: Yinyue Deng, Amy Lim, Jasmine Lee, Shaohua Chen, Shuwen An, Yi-Hu Dong and Lian-Hui Zhang
    Citation: BMC Microbiology 2014 14:51
    Content type: Research article Published on:

  4. Rhodosporidium toruloides is a β-carotenoid accumulating, oleaginous yeast that has great biotechnological potential. The lack of reliable and efficient genetic manipulation tools have been a major hurdle blocki...

    Authors: Chong Mei John Koh, Yanbin Liu, Moehninsi, Minge Du and Lianghui Ji
    Citation: BMC Microbiology 2014 14:50
    Content type: Research article Published on:

  5. Pathogenic serotypes of Vibrio cholerae cause the life-threatening diarrheal disease cholera. The increasing development of bacterial resistances against the known antibiotics necessitates the search for new anti...

    Authors: Galina Sergeev, Sambit Roy, Michael Jarek, Viktor Zapolskii, Dieter E Kaufmann, Ranjan K Nandy and Werner Tegge
    Citation: BMC Microbiology 2014 14:49
    Content type: Research article Published on:

  6. To obtain insights into Escherichia coli O157:H7 (O157) survival mechanisms in the bovine rumen, we defined the growth characteristics and proteome of O157 cultured in rumen fluid (RF; pH 6.0-7.2 and low volatile...

    Authors: Indira T Kudva, Thaddeus B Stanton and John D Lippolis
    Citation: BMC Microbiology 2014 14:48
    Content type: Research article Published on:

  7. Haemophilus influenzae colonizes the nasopharynx as a commensal. Strain-specific factors allow some strains to migrate to particular anatomical niches, such as the middle ear, bronchi or blood, and induce diseas...

    Authors: Nadiah Ishak, Alexandra Tikhomirova, Stephen J Bent, Garth D Ehrlich, Fen Z Hu and Stephen P Kidd
    Citation: BMC Microbiology 2014 14:47
    Content type: Research article Published on:

  8. The antimetabolite mangotoxin is a key factor in virulence of Pseudomonas syringae pv. syringae strains which cause apical necrosis of mango trees. Previous studies showed that mangotoxin biosynthesis is governed...

    Authors: Víctor J Carrión, Menno van der Voort, Eva Arrebola, José A Gutiérrez-Barranquero, Antonio de Vicente, Jos M Raaijmakers and Francisco M Cazorla
    Citation: BMC Microbiology 2014 14:46
    Content type: Research article Published on:

  10. Dengue virus (DENV) still poses a global public health threat, and no vaccine or antiviral therapy is currently available. Antibody plays distinct roles in controlling DENV infections. Neutralizing antibody is...

    Authors: Ke-Yu Song, Hui Zhao, Zhen-You Jiang, Xiao-Feng Li, Yong-Qiang Deng, Tao Jiang, Shun-Ya Zhu, Pei-Yong Shi, Bo Zhang, Fu-Chun Zhang, E-De Qin and Cheng-Feng Qin
    Citation: BMC Microbiology 2014 14:44
    Content type: Research article Published on:

  11. Imbalanced feeding regimes may initiate gastrointestinal and metabolic diseases in endangered felids kept in captivity such as cheetahs. Given the crucial role of the host’s intestinal microbiota in feed ferme...

    Authors: Anne AMJ Becker, Myriam Hesta, Joke Hollants, Geert PJ Janssens and Geert Huys
    Citation: BMC Microbiology 2014 14:43
    Content type: Research article Published on:

  12. Laribacter hongkongensis is a Gram-negative, urease-positive bacillus associated with invasive bacteremic infections in liver cirrhosis patients and fish-borne community-acquired gastroenteritis and traveler’s d...

    Authors: Lifeng Xiong, Jade LL Teng, Rory M Watt, Biao Kan, Susanna KP Lau and Patrick CY Woo
    Citation: BMC Microbiology 2014 14:42
    Content type: Research article Published on:

  13. Coxiella burnetii causes Q fever in humans and Coxiellosis in animals; symptoms range from general malaise to fever, pneumonia, endocarditis and death. Livestock are a significant source of human infection as th...

    Authors: Talima Pearson, Heidie M Hornstra, Remy Hilsabeck, Lauren T Gates, Sonora M Olivas, Dawn M Birdsell, Carina M Hall, Sabrina German, James M Cook, Meagan L Seymour, Rachael A Priestley, Ashley V Kondas, Christine L Clark Friedman, Erin P Price, James M Schupp, Cindy M Liu…
    Citation: BMC Microbiology 2014 14:41
    Content type: Research article Published on:

  14. Chlamydia trachomatis is an obligate intracellular human pathogen causing ocular and urogenital infections that are a significant clinical and public health concern. This bacterium uses a type III secretion (T3S...

    Authors: Maria da Cunha, Catarina Milho, Filipe Almeida, Sara V Pais, Vítor Borges, Rui Maurício, Maria José Borrego, João Paulo Gomes and Luís Jaime Mota
    Citation: BMC Microbiology 2014 14:40
    Content type: Research article Published on:

  15. Huanglongbing (HLB) or citrus greening is a devastating disease of citrus. The gram-negative bacterium Candidatus Liberibacter asiaticus (Las) belonging to the α-proteobacteria is responsible for HLB in North Ame...

    Authors: Sunitha Kogenaru, Qing Yan, Nadia Riera, M Caroline Roper, Xiaoling Deng, Timothy A Ebert, Michael Rogers, Michael E Irey, Gerhard Pietersen, Charles M Rush and Nian Wang
    Citation: BMC Microbiology 2014 14:39
    Content type: Research article Published on:

  16. The aim of this paper was to develop a reverse transcription loop-mediated isothermal amplification (RT-LAMP) method for rapid, sensitive and inexpensive detection of astrovirus.

    Authors: Bo-Yun Yang, Xiao-Lu Liu, Yu-Mei Wei, Jing-Qi Wang, Xiao-Qing He, Yi Jin and Zi-Jian Wang
    Citation: BMC Microbiology 2014 14:38
    Content type: Research article Published on:

  17. Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an imp...

    Authors: Qing-Lin Meng, Fei Liu, Xing-Yuan Yang, Xiao-Mei Liu, Xia Zhang, Chun Zhang and Zong-De Zhang
    Citation: BMC Microbiology 2014 14:37
    Content type: Research article Published on:

  18. The raw goat milk microbiota is considered a good source of novel bacteriocinogenic lactic acid bacteria (LAB) strains that can be exploited as an alternative for use as biopreservatives in foods. The constant...

    Authors: Luana Martins Perin and Luís Augusto Nero
    Citation: BMC Microbiology 2014 14:36
    Content type: Research article Published on:

  19. A wealth of microbial eukaryotes is adapted to life in oxygen-deficient marine environments. Evidence is accumulating that some of these eukaryotes survive anoxia by employing dissimilatory nitrate reduction, ...

    Authors: Peter Stief, Silvia Fuchs-Ocklenburg, Anja Kamp, Cathrine-Sumathi Manohar, Jos Houbraken, Teun Boekhout, Dirk de Beer and Thorsten Stoeck
    Citation: BMC Microbiology 2014 14:35
    Content type: Research article Published on:

  20. In this study we employed the TAP tag purification method coupled with mass spectrometry analysis to identify proteins that co-purify with Escherichia coli RNase R during exponential growth and after temperature ...

    Authors: Michal Malecki, Cátia Bárria and Cecilia M Arraiano
    Citation: BMC Microbiology 2014 14:34
    Content type: Research article Published on:

  23. The community-associated methicillin-resistant S. aureus (CA-MRSA) ST93 clone is becoming dominant in Australia and is clinically highly virulent. In addition, sepsis and skin infection models demonstrate that ST...

    Authors: Kyra YL Chua, Ian R Monk, Ya-Hsun Lin, Torsten Seemann, Kellie L Tuck, Jessica L Porter, Justin Stepnell, Geoffrey W Coombs, John K Davies, Timothy P Stinear and Benjamin P Howden
    Citation: BMC Microbiology 2014 14:31
    Content type: Research article Published on:

  24. Polyoxypeptin A was isolated from a culture broth of Streptomyces sp. MK498-98 F14, which has a potent apoptosis-inducing activity towards human pancreatic carcinoma AsPC-1 cells. Structurally, polyoxypeptin A is...

    Authors: Yanhua Du, Yemin Wang, Tingting Huang, Meifeng Tao, Zixin Deng and Shuangjun Lin
    Citation: BMC Microbiology 2014 14:30
    Content type: Research article Published on:

  25. In an effort to reconstitute the NAD+ synthetic pathway in Escherichia coli (E. coli), we produced a set of gene knockout mutants with deficiencies in previously well-defined NAD+ de novo and salvage pathways. Un...

    Authors: Wei-Ren Dong, Cen-Cen Sun, Guan Zhu, Shi-Hua Hu, Li-Xin Xiang and Jian-Zhong Shao
    Citation: BMC Microbiology 2014 14:29
    Content type: Research article Published on:

  26. Lactobacillus rhamnosus is a non-starter lactic acid bacterium that plays a significant role during cheese ripening, leading to the formation of flavor. In long-ripened cheeses it persists throughout the whole t...

    Authors: Camilla Lazzi, Silvia Turroni, Andrea Mancini, Elisa Sgarbi, Erasmo Neviani, Patrizia Brigidi and Monica Gatti
    Citation: BMC Microbiology 2014 14:28
    Content type: Research article Published on:

  27. Mycoplasma pneumoniae (M. pneumoniae) is one of the major etiological agents for community-acquired pneumonia (CAP) in all age groups. The early host response to M. pneumoniae infection relies on the concerted r...

    Authors: Shuxian Li, Xuejing Li, Yingshuo Wang, Jun Yang, Zhimin Chen and Shigang Shan
    Citation: BMC Microbiology 2014 14:27
    Content type: Research article Published on:

  28. Pyocyanin (PCN), an extracellular product of Pseudomonas aeruginosa and a blue redox active secondary metabolite, plays an important role in invasive pulmonary infection. However, the detailed inflammatory respon...

    Authors: Wenshu Chai, Jia Zhang, Yan Duan, Dianzhu Pan, Wei Liu, Ying Li, Xue Yan and Baiyi Chen
    Citation: BMC Microbiology 2014 14:26
    Content type: Research article Published on:

  29. The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based ap...

    Authors: Fiona Fouhy, R Paul Ross, Gerald F Fitzgerald, Catherine Stanton and Paul D Cotter
    Citation: BMC Microbiology 2014 14:25
    Content type: Research article Published on:

  30. Antibiotics in current use target a surprisingly small number of cellular functions: cell wall, DNA, RNA, and protein biosynthesis. Targeting of novel essential pathways is expected to play an important role i...

    Authors: Ruggero Rusmini, Davide Vecchietti, Raffaella Macchi, Faustino Vidal-Aroca and Giovanni Bertoni
    Citation: BMC Microbiology 2014 14:24
    Content type: Research article Published on:

  31. Histoplasma capsulatum and Pneumocystis organisms cause host infections primarily affecting the lung tissue. H. capsulatum is endemic in the United States of America and Latin American countries. In special envi...

    Authors: Antonio E González-González, Cécile M Aliouat-Denis, José A Ramírez-Bárcenas, Christine Demanche, Muriel Pottier, Laura E Carreto-Binaghi, Haroon Akbar, Sandra Derouiche, Magalie Chabé, El Moukhtar Aliouat, Eduardo Dei-Cas and Maria Lucia Taylor
    Citation: BMC Microbiology 2014 14:23
    Content type: Research article Published on:

  32. Diguanylate cyclases (DGCs) regulate biofilm formation and motility in bacteria by synthesizing the second messenger cyclic di-GMP (c-di-GMP) in response to environmental stimuli. DGC enzymatic activity is bel...

    Authors: Jessica L Hunter, Geoffrey B Severin, Benjamin J Koestler and Christopher M Waters
    Citation: BMC Microbiology 2014 14:22
    Content type: Research article Published on:

  33. Different polymorphisms have been described as markers to classify the lineages of the Mycobacterium tuberculosis complex. The analysis of nine single nucleotide polymorphisms (SNPs) was used to describe seven SN...

    Authors: Adriana Cabal, Mark Strunk, José Domínguez, María Antonia Lezcano, María Asunción Vitoria, Miguel Ferrero, Carlos Martín, María José Iglesias and Sofía Samper
    Citation: BMC Microbiology 2014 14:21
    Content type: Research article Published on:

  34. Celiac disease is characterized by enhanced intestinal paracellular permeability due to alterations of function and expression of tight junction (TJ) proteins including ZO-1, Claudin-1 and Occludin. Polyamines...

    Authors: Antonella Orlando, Michele Linsalata, Maria Notarnicola, Valeria Tutino and Francesco Russo
    Citation: BMC Microbiology 2014 14:19
    Content type: Research article Published on:

  35. Filamentous fungi produce small cysteine rich surface active amphiphilic hydrophobins on the outer surface of cell walls that mediate interactions between the fungus and the environment. The role of hydrophobi...

    Authors: Mukesh K Dubey, Dan Funck Jensen and Magnus Karlsson
    Citation: BMC Microbiology 2014 14:18
    Content type: Research article Published on:

  36. The editors of BMC Microbiology would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).

    Authors: Philippa K Harris
    Citation: BMC Microbiology 2014 14:20
    Content type: Reviewer acknowledgement Published on:

  37. Stenotrophomonas maltophilia is a ubiquitous Gram-negative bacterium previously named as Xanthomonas maltophilia. This organism is an important nosocomial pathogen associated with infections in immunocompromised...

    Authors: Chia-Ni Lee, Tsai-Tien Tseng, Hsiao-Chuan Chang, Juey-Wen Lin and Shu-Fen Weng
    Citation: BMC Microbiology 2014 14:17
    Content type: Research article Published on:

  38. The Escherichia coli uropathogenic-specific protein (Usp) is a bacteriocin-like genotoxin, active against mammalian cells and associated with E. coli strains that provoke pyelonephritis, prostatitis and bacteraem...

    Authors: Miha Črnigoj, Zdravko Podlesek, Maruška Budič and Darja Žgur-Bertok
    Citation: BMC Microbiology 2014 14:16
    Content type: Research article Published on:

  39. Internalin A (InlA) facilitates the invasion of Listeria monocytogenes into a host cell. Some strains of Listeria monocytogenes express truncated forms of InlA, which reduces invasiveness. However, few virulence-...

    Authors: Daisuke Kyoui, Hajime Takahashi, Satoko Miya, Takashi Kuda and Bon Kimura
    Citation: BMC Microbiology 2014 14:15
    Content type: Research article Published on:

  40. Publicly available expression compendia that measure both mRNAs and sRNAs provide a promising resource to simultaneously infer the transcriptional and the posttranscriptional network. To maximally exploit the ...

    Authors: Ivan Ishchukov, Yan Wu, Sandra Van Puyvelde, Jos Vanderleyden and Kathleen Marchal
    Citation: BMC Microbiology 2014 14:14
    Content type: Research article Published on:

  41. Multidrug efflux pumps are membrane translocases that have the ability to extrude a variety of structurally unrelated compounds from the cell. AcrD, a resistance-nodulation-cell division (RND) transporter, was...

    Authors: Daniel Pletzer and Helge Weingart
    Citation: BMC Microbiology 2014 14:13
    Content type: Research article Published on:

  42. Penicillin-resistance in Streptococcus pneumoniae is mainly due to alterations in genes encoding the target enzymes for beta-lactams, the penicillin-binding proteins (PBPs). However, non-PBP genes are altered in ...

    Authors: Marina Meiers, Carsten Volz, Jessica Eisel, Patrick Maurer, Bernhard Henrich and Regine Hakenbeck
    Citation: BMC Microbiology 2014 14:12
    Content type: Research article Published on:

  43. Gene gain and loss frequently occurs in the cyanobacterium Prochlorococcus, a phototroph that numerically dominates tropical and subtropical open oceans. However, little is known about the stabilization of its co...

    Authors: Bang Wang, Lina Lu, Hexin Lv, Huifeng Jiang, Ge Qu, Chaoguang Tian and Yanhe Ma
    Citation: BMC Microbiology 2014 14:11
    Content type: Research article Published on:

  44. Capripox viruses are economically important pathogens in goat and sheep producing areas of the world, with specific focus on goat pox virus (GTPV), sheep pox virus (SPPV) and the Lumpy Skin Disease virus (LSDV...

    Authors: Zhixun Zhao, Bin Fan, Guohua Wu, Xinmin Yan, Yingguo Li, Xiaoli Zhou, Hua Yue, Xueling Dai, Haixia Zhu, Bo Tian, Jian Li and Qiang Zhang
    Citation: BMC Microbiology 2014 14:10
    Content type: Methodology article Published on:

  45. The global epidemiology of parasitic helminths and mycobacterial infections display extensive geographical overlap, especially in the rural and urban communities of developing countries. We investigated whethe...

    Authors: Hendrik J Nel, Nelita du Plessis, Leanie Kleynhans, André G Loxton, Paul D van Helden and Gerhard Walzl
    Citation: BMC Microbiology 2014 14:9
    Content type: Research article Published on:

  46. Visceral leishmaniasis caused by the protozoan parasite Leishmania donovani complex is a potentially fatal disease if left untreated. Few treatment options exist and are toxic, costly and ineffective against resi...

    Authors: Sudipta Bhowmick, Rajesh Ravindran and Nahid Ali
    Citation: BMC Microbiology 2014 14:8
    Content type: Research article Published on:

  47. Transketolase (TKT) is a key enzyme of the pentose phosphate pathway (PPP), the Calvin cycle and the ribulose monophosphate (RuMP) cycle. Bacillus methanolicus is a facultative RuMP pathway methylotroph. B. metha...

    Authors: Benno Markert, Jessica Stolzenberger, Trygve Brautaset and Volker F Wendisch
    Citation: BMC Microbiology 2014 14:7
    Content type: Research article Published on:

  48. Rhizobium grahamii belongs to a new phylogenetic group of rhizobia together with Rhizobium mesoamericanum and other species. R. grahamii has a broad-host-range that includes Leucaena leucocephala and Phaseolus v...

    Authors: María Julia Althabegoiti, Ernesto Ormeño-Orrillo, Luis Lozano, Gonzalo Torres Tejerizo, Marco Antonio Rogel, Jaime Mora and Esperanza Martínez-Romero
    Citation: BMC Microbiology 2014 14:6
    Content type: Research article Published on:

  49. Shiga toxin-producing Escherichia coli (STEC) is recognized as an important human diarrheal pathogen. Swine plays an important role as a carrier of this pathogen. In this study we determined the prevalence and ch...

    Authors: Qiong Meng, Xiangning Bai, Ailan Zhao, Ruiting Lan, Huamao Du, Tao Wang, Changyou Shi, Xuejiao Yuan, Xuemei Bai, Shaobo Ji, Dong Jin, Bo Yu, Yan Wang, Hui Sun, Kai Liu, Jianguo Xu…
    Citation: BMC Microbiology 2014 14:5
    Content type: Research article Published on:

  50. Metarhizium anisopliae, a soil-borne entomopathogen found worldwide, is an interesting fungus for biological control. However, its efficacy in the fields is significantly affected by environmental conditions, pa...

    Authors: Zi-Hong Chen, Ling Xu, Feng-lian Yang, Guang-Hai Ji, Jing Yang and Jian-Yun Wang
    Citation: BMC Microbiology 2014 14:4
    Content type: Research article Published on:
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BMC Microbiology

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