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  1. Content type: Research article

    A major obstacle to industrial-scale astaxanthin production by the yeast Phaffia rhodozyma is the strong inhibitory effect of high glucose concentration on astaxanthin synthesis. We investigated, for the first ti...

    Authors: Lili Miao, Shuang Chi, Mengru Wu, Zhipei Liu and Ying Li

    Citation: BMC Microbiology 2019 19:133

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  2. Content type: Research article

    Xenorhabdus spp. live in close symbiosis with nematodes of the Steinernema genus. Steinernema nematodes infect an insect larva and release their symbionts into the haemocoel of the insect. Once released into the ...

    Authors: J. Dreyer, M. Rautenbach, E. Booysen, A. D. van Staden, S. M. Deane and L. M. T. Dicks

    Citation: BMC Microbiology 2019 19:132

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  3. Content type: Research article

    The Latin American & Mediterranean (LAM) spoligotype family is one of the most successful genotype of Mycobacterium tuberculosis worldwide and particularly prevalent in South-America. Within this family, a sublin...

    Authors: Chyntia Carolina Díaz Acosta, Graciela Russomando, Norma Candia, Viviana Ritacco, Sidra E. G. Vasconcellos, Marcia de Berrêdo Pinho Moreira, Nilda J. de Romero, Nora Morcillo, Jacobus Henri De Waard, Harrison Magdinier Gomes and Philip Noel Suffys

    Citation: BMC Microbiology 2019 19:131

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  4. Content type: Research article

    Treatment with the α-glucosidase inhibitor acarbose increases median lifespan by approximately 20% in male mice and 5% in females. This longevity extension differs from dietary restriction based on a number of fe...

    Authors: Byron J Smith, Richard A Miller, Aaron C Ericsson, David C Harrison, Randy Strong and Thomas M Schmidt

    Citation: BMC Microbiology 2019 19:130

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  5. Content type: Research article

    Enteric methane from the ruminant livestock is a significant source in global greenhouse gas emissions, which is mainly generated by the methanogens inhabiting the rumen and cecum. Sika deer (Cervus nippon) not o...

    Authors: Zhipeng Li, Xiaoxu Wang, Ting Zhang, Huazhe Si, Chao Xu, André-Denis G. Wright and Guangyu Li

    Citation: BMC Microbiology 2019 19:129

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  6. Content type: Research article

    RNA-binding proteins (RBPs) are well known as key factors in gene expression regulation in eukaryotes. These proteins associate with mRNAs and other proteins to form mRNP complexes that ultimately determine th...

    Authors: Helisa Helena Wippel, Juliane Soldi Malgarin, Alexandre Haruo Inoue, Felipe da Veiga Leprevost, Paulo Costa Carvalho, Samuel Goldenberg and Lysangela Ronalte Alves

    Citation: BMC Microbiology 2019 19:128

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  7. Content type: Research article

    Porphyromonas gingivalis is considered a keystone pathogen responsible for chronic periodontitis. Although several virulence factors produced by this bacterium are quite well characterized, very little is known a...

    Authors: Michał Śmiga, Paulina Stępień, Mariusz Olczak and Teresa Olczak

    Citation: BMC Microbiology 2019 19:127

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  8. Content type: Research article

    Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA’s virulence and resistance mechanisms is a continuing concern toward controllin...

    Authors: Mohamed S. Ali, Nurulfiza M. Isa, Faisal M. Abedelrhman, Tahani B. Alyas, Sara E. Mohammed, Abdallah E. Ahmed, Zainab S. A. Ahmed, Nyok-Sean Lau, Mohamed I. Garbi, Abdullah Al-Ashraf Amirul, Almeen O. Seed, Rihab A. Omer and Sofia B. Mohamed

    Citation: BMC Microbiology 2019 19:126

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  9. Content type: Research article

    Pseudorabies virus (PRV, or suid herpesvirus, SuHV-1), a member of the herpesvirus family, has an extremely broad host range and threatens the pig industry in China. PRV can evade host innate immunity and infe...

    Authors: Yi Fan, Ling Zhu, Xiangang Sun, Wenting Lyu, Lei Xu, Yue Yin, Jun Zhao, Jianbo Huang, Yichao Den, Zhiyi Jiang, Shiyao Xu, Xiyu Mao and Zhiwen Xu

    Citation: BMC Microbiology 2019 19:125

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  10. Content type: Research article

    Macrolides and lincosamides are two leading types of antibiotics commonly used in therapies. The study examines the differences in resistance to these antibiotics and their molecular bases in S. epidermidis as we...

    Authors: Magdalena Szemraj, Tomasz Czekaj, Jacek Kalisz and Eligia M. Szewczyk

    Citation: BMC Microbiology 2019 19:124

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  11. Content type: Research article

    Gut microbes have been suggested as the possible targets in the management of allergic diseases. However, the way in which these microbes influence allergic diseases remain unclear. Forty-seven full-term newbo...

    Authors: Xi Shen, Maolin Wang, Xiao Zhang, Miao He, Ming Li, Guo Cheng, Chaomin Wan and Fang He

    Citation: BMC Microbiology 2019 19:123

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  12. Content type: Research article

    Acinetobacter baumannii is a cosmopolitan bacterium that is frequently reported from hospitalized patients, especially those patients who admitted in the intensive care unit. Recently, multiplex real-time PCR has...

    Authors: Hossein Goudarzi, Elnaz Sadat Mirsamadi, Zohreh Ghalavand, Mojdeh Hakemi Vala, Hamed Mirjalali and Ali Hashemi

    Citation: BMC Microbiology 2019 19:122

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  13. Content type: Research article

    Bluetongue virus (BTV) causes a disease among wild and domesticated ruminants which is not contagious, but which is transmitted by biting midges of the Culicoides species. BTV can induce an intense cytopathic eff...

    Authors: Junzheng Du, Shandian Gao, Zhancheng Tian, Yanni Guo, Di Kang, Shanshan Xing, Guorui Zhang, Guangyuan Liu, Jianxun Luo, Huiyun Chang and Hong Yin

    Citation: BMC Microbiology 2019 19:121

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  14. Content type: Research article

    There are numerous advantages offered by street vended foods, but evidence exists that foods exposed for sale on the road side may be contaminated by pathogenic microorganisms. However, information on the bact...

    Authors: Azanaw Amare, Tifito Worku, Birukitait Ashagirie, Marie Adugna, Alem Getaneh and Mulat Dagnew

    Citation: BMC Microbiology 2019 19:120

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  15. Content type: Research article

    Ready-to-eat (RTE) vegetables have become increasingly popular along with the trend of moving towards a healthy lifestyle. However, RTE vegetables are at a higher risk of containing pathogens, maybe owing to l...

    Authors: Moutong Chen, Yuetao Chen, Qingping Wu, Jumei Zhang, Jianheng Cheng, Fan Li, Haiyan Zeng, Tao Lei, Rui Pang, Qinghua Ye, Jianling Bai, Juan Wang, Xianhu Wei, Youxiong Zhang and Yu Ding

    Citation: BMC Microbiology 2019 19:119

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  16. Content type: Research article

    Clostridium cellulovorans is a mesophilic, cellulosome-producing bacterium containing 57 genomic cellulosomal enzyme-encoding genes. In addition to cellulosomal proteins, C. cellulovorans also secretes non-cellul...

    Authors: Shunsuke Aburaya, Wataru Aoki, Kouichi Kuroda, Hiroshi Minakuchi and Mitsuyoshi Ueda

    Citation: BMC Microbiology 2019 19:118

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  17. Content type: Research article

    The Escherichia coli sequence type 131 (ST131) is a well established clone causing significant extraintestinal infections worldwide. However, no studies have been reported the phenotypic and molecular traits of S...

    Authors: Zoya Hojabri, Narges Darabi, Maedeh Arab, Fereshteh Saffari and Omid Pajand

    Citation: BMC Microbiology 2019 19:117

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  18. Content type: Research article

    Shigella spp., facultative anaerobic bacilli of the family Enterobacteriaceae, are one of the most common causes of diarrheal diseases in human worldwide which have become a significant public health burden. So, ...

    Authors: Yang Wang, Qiuxia Ma, Ruie Hao, Qiuxiang Zhang, Suxia Yao, Jiting Han, Binzhi Ren, Ting Fan, Limin Chen, Xuebin Xu, Shaofu Qiu and Hongxia Yang

    Citation: BMC Microbiology 2019 19:116

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  19. Content type: Research article

    Although the most widely accepted mechanism of action for polymyxins is related to bacterial lysis via disruption, we hypothesized that this antimicrobial drug class could have other effects on Pseudomonas aerugi...

    Authors: Marlucy Rodrigues Lima, Gabriella Freitas Ferreira, Wallace Ribeiro Nunes Neto, Joveliane de Melo Monteiro, Áquila Rodrigues Costa Santos, Priscila Batista Tavares, Ângelo Márcio Leite Denadai, Maria Rosa Quaresma Bomfim, Vera Lúcia dos Santos, Sirlei Garcia Marques and Andrea de Souza Monteiro

    Citation: BMC Microbiology 2019 19:115

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  20. Content type: Research article

    Methicillin-resistant Staphylococcus aureus (MRSA) biofilm producers represent an important etiological agent of many chronic human infections. Antibiotics and host immune responses are largely ineffective agains...

    Authors: Khulood Hamid Dakheel, Raha Abdul Rahim, Vasantha Kumari Neela, Jameel R. Al-Obaidi, Tan Geok Hun, Mohd Noor Mat Isa and Khatijah Yusoff

    Citation: BMC Microbiology 2019 19:114

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  21. Content type: Research article

    Trichosporon is the dominant genus of epidermal fungi in giant pandas (Ailuropoda melanoleuca) and causes local and deep infections. To provide the information needed for the diagnosis and treatment of trichospor...

    Authors: Xiaoping Ma, Yaozhang Jiang, Chengdong Wang, Yu Gu, Sanjie Cao, Xiaobo Huang, Yiping Wen, Qin Zhao, Rui Wu, Xintian Wen, Qigui Yan, Xinfeng Han, Zhicai Zuo, Junliang Deng, Zhihua Ren, Shumin Yu…

    Citation: BMC Microbiology 2019 19:113

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  22. Content type: Research article

    Gut bacteria are an important component of the microbiota ecosystem in humans and other animals, and they play important roles in human health. The aim of this study was to investigate the relationship between...

    Authors: Wu Enqi, Zhao Huanhu, Wu Ritu, Xie Dan, Lin Han, Wang Baili, Shen Gangyi and Li Shuchun

    Citation: BMC Microbiology 2019 19:111

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  23. Content type: Research article

    Knowledge of microbiota composition, persistence, and transmission as well as the overall function of the bacterial community is important and may be linked to honey bee health. This study aimed to investigate...

    Authors: Zuzana Hroncova, Jiri Killer, Josef Hakl, Dalibor Titera and Jaroslav Havlik

    Citation: BMC Microbiology 2019 19:110

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  24. Content type: Research article

    The abuse of antibiotics in animal husbandry imposes a serious threat to both animal health and the environment. As a replacement for antibiotics, probiotic products have been widely used in livestock farming ...

    Authors: Yongjia Peng, Qiumei Shi, Yujie Wang, Fan Zhang, Zhixin Ji and Jin Zhang

    Citation: BMC Microbiology 2019 19:109

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  25. Content type: Research article

    Infection with Brucella melitensis (B. melitensis) is one of the most important causes of abortion in goats and sheep, and also causes severe systemic disease in exposed humans. In Ethiopia, based on seroepidemio...

    Authors: Muluken Tekle, Mengistu Legesse, Bedaso Mammo Edao, Gobena Ameni and Gezahegne Mamo

    Citation: BMC Microbiology 2019 19:108

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  26. Content type: Research article

    Riemerella anatipestifer (R. anatipestifer) is one of the most important poultry pathogens worldwide, with associated infections causing significant economic losses. Rifampin Resistance is an important mechanism ...

    Authors: Jiakai Sun, Dekang Zhu, Jinge Xu, Renyong Jia, Shun Chen, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Yunya Liu, Ling Zhang, Yanling Yu, Yu You, Mingshu Wang and Anchun Cheng

    Citation: BMC Microbiology 2019 19:107

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  27. Content type: Research article

    The introduction of MALDI-TOF MS in the clinical microbiology laboratory has modified the approaches for the identification of fungi. Thanks to this tool, it is possible to identify cryptic species, which poss...

    Authors: Andrés Ceballos-Garzón, Gloria Cortes, Florent Morio, Edna L. Zamora-Cruz, Melva Y. Linares, Beatriz E. Ariza, Sandra L. Valderrama, Javier R. Garzón, Carlos A. Alvarez-Moreno, Patrice Le Pape and Claudia M. Parra-Giraldo

    Citation: BMC Microbiology 2019 19:106

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  28. Content type: Research article

    Over the past few decades, most attention to Chinese Cordyceps-associated endogenous microorganism was focused on the fungal community that creates critical bioactive components. Bacterial community associated...

    Authors: Fei Xia, Xin Zhou, Yan Liu, Yuling Li, Xiaohui Bai and Xuanwei Zhou

    Citation: BMC Microbiology 2019 19:105

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  29. Content type: Research article

    Vitamin B1 (VB1) is a crucial dietary nutrient and essential cofactor for several key enzymes in the regulation of cellular and metabolic processes, and more importantly in the activation of immune system. To dat...

    Authors: Ningning Song, Zhaoli Li, Ziyin Cui, Liping Chen, Yingying Cui, Guanghui Dang, Zhe Li, He Li and Siguo Liu

    Citation: BMC Microbiology 2019 19:104

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  30. Content type: Research article

    Hfq is a widely conserved bacterial RNA-binding protein which generally mediates the global regulatory activities involv ed in physiological process and virulence. The goal of this study was to characterize th...

    Authors: Xuelu Liu, Yuping Yan, Haodi Wu, Changyong Zhou and Xuefeng Wang

    Citation: BMC Microbiology 2019 19:103

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  31. Content type: Research article

    The newly created associations of lactic acid bacteria (LAB) isolated from Armenian dairy products (yoghurt, sour cream and different varieties of cheese), as well as from the gastrointestinal tract of honeybe...

    Authors: Lusine Matevosyan, Inga Bazukyan and Armen Trchounian

    Citation: BMC Microbiology 2019 19:102

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  32. Content type: Research article

    Bacterial chemotaxis, the ability of motile bacteria to navigate gradients of chemicals, plays key roles in the establishment of various plant-microbe associations, including those that benefit plant growth an...

    Authors: Mustafa Elmas, Vasilios Alexiades, Lindsey O’Neal and Gladys Alexandre

    Citation: BMC Microbiology 2019 19:101

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  33. Content type: Research article

    Thermotolerance is a highly desirable trait of microbial cell factories and has been the focus of extensive research. Yeast usually tolerate only a narrow temperature range and just two species, Kluyveromyces mar...

    Authors: Mathias Lehnen, Birgitta E. Ebert and Lars M. Blank

    Citation: BMC Microbiology 2019 19:100

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  34. Content type: Research article

    Consuming red and processed meat has been associated with an increased risk of colorectal cancer (CRC), which is partly attributed to exposure to carcinogens such as heterocyclic amines (HCA) formed during coo...

    Authors: Jianbo Zhang, Christophe Lacroix, Esther Wortmann, Hans-Joachim Ruscheweyh, Shinichi Sunagawa, Shana J. Sturla and Clarissa Schwab

    Citation: BMC Microbiology 2019 19:99

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  35. Content type: Research article

    Burkholderia pseudomallei is a human pathogen causing severe infections in tropical and subtropical regions and is classified as a bio-threat agent. B. thailandensis strain E264 has been proposed as less pathogen...

    Authors: A. Kovacs-Simon, C. M. Hemsley, A. E. Scott, J. L. Prior and R. W. Titball

    Citation: BMC Microbiology 2019 19:97

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  36. Content type: Research article

    Staphylococcus aureus (S. aureus) with accessory gene regulator (agr) dysfunction occurs in health care settings. This study evaluated the prevalence and the molecular and drug resistance characteristics of S. au...

    Authors: Xin Yang, Fang Dong, Suyun Qian, Lijuan Wang, Yingchao Liu, Kaihu Yao, Wenqi Song, Jinghui Zhen, Wei Zhou, Hong Xu and Hongyan Zheng

    Citation: BMC Microbiology 2019 19:95

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  37. Content type: Methodology article

    Obtaining sufficient RNA yield and quality for comprehensive transcriptomic studies is cumbersome for clinical samples in which RNA from the pathogen is present in low numbers relative to the nucleic acids fro...

    Authors: Antonio Rodríguez and Mario Vaneechoutte

    Citation: BMC Microbiology 2019 19:94

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  38. Content type: Research article

    Fast molecular detection methods benefit from ready-to-run lab-on-a-chip molecular assays with minimum preparation time. Detection efficiency of such methods can improve if multiple targets are detected simult...

    Authors: Dammika P. Manage, Jana Lauzon, Lynn M. McMullen and Linda M. Pilarski

    Citation: BMC Microbiology 2019 19:93

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  39. Content type: Research article

    Cathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors – cystatins. Cathepsins are crucial t...

    Authors: Magdalena Bossowska-Nowicka, Matylda B. Mielcarska, Marta Romaniewicz, Monika M. Kaczmarek, Karolina P. Gregorczyk-Zboroch, Justyna Struzik, Marta Grodzik, Małgorzata M. Gieryńska, Felix N. Toka and Lidia Szulc-Dąbrowska

    Citation: BMC Microbiology 2019 19:92

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  40. Content type: Research article

    Candidatus Berkiella cookevillensis’ and ‘Ca. Berkiella aquae’ have previously been described as intranuclear bacteria of amoebae. Both bacteria were isolated from amoebae and were described as appearing within...

    Authors: Nicholas B. Chamberlain, Yohannes T. Mehari, B. Jason Hayes, Colleen M. Roden, Destaalem T. Kidane, Andrew J. Swehla, Mario A. Lorenzana-DeWitt, Anthony L. Farone, John H. Gunderson, Sharon G. Berk and Mary B. Farone

    Citation: BMC Microbiology 2019 19:91

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  41. Content type: Research article

    Statistical evaluation of the association between microbial abundance and dietary variables can be done in various ways. Currently, there is no consensus on which methods are to be preferred in which circumsta...

    Authors: Xiang Zhang, Max Nieuwdorp, Albert K. Groen and Aeiko H. Zwinderman

    Citation: BMC Microbiology 2019 19:90

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  42. Content type: Research article

    Nattokinase (NK), which is a member of the subtilisin family, is a potent fibrinolytic enzyme that might be useful for thrombosis therapy. Extensive work has been done to improve its production for the food in...

    Authors: Zhongmei Liu, Wenhui Zheng, Chunlei Ge, Wenjing Cui, Li Zhou and Zhemin Zhou

    Citation: BMC Microbiology 2019 19:89

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  43. Content type: Research article

    Lactococcus lactis strain Plasma (LC-Plasma) possesses strong stimulatory activity for plasmacytoid dendritic cells (pDCs) via the TLR9-Myd88 pathway. To reveal the effective lactic acid bacteria (LAB) genome str...

    Authors: Akira Horie, Yasuyuki Tomita, Konomi Ohshio, Daisuke Fujiwara and Toshio Fujii

    Citation: BMC Microbiology 2019 19:88

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  44. Content type: Research article

    Both phylogeny and functional capabilities within the gut microbiota populations are of great importance for influencing host health. As a novel type of resistant starch, transglycosylated starch (TGS) modifie...

    Authors: Barbara U. Metzler-Zebeli, Monica A. Newman, Dietmar Grüll and Qendrim Zebeli

    Citation: BMC Microbiology 2019 19:87

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  45. Content type: Research article

    Anopheles mosquitoes are of great importance to human health. A number of studies have shown that midgut and salivary gland microflora have an impact on malaria parasite burden through colonization mechanisms, in...

    Authors: Abib Berhanu, Adugna Abera, Desalegn Nega, Sindew Mekasha, Surafel Fentaw, Abebe Assefa, Gashaw Gebrewolde, Yonas Wuletaw, Ashenafi Assefa, Sisay Dugassa, Habte Tekie and Geremew Tasew

    Citation: BMC Microbiology 2019 19:85

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  46. Content type: Research article

    The hydrophobic nature of hydrocarbons make them less bioavailable to microbes, generally leading to low efficiency in biodegradation. Current bioremediation strategies for hydrocarbon contamination, uses indu...

    Authors: Madushika Perera, Dilrukshi Wijayarathna, Sulochana Wijesundera, Manoj Chinthaka, Gamini Seneviratne and Sharmila Jayasena

    Citation: BMC Microbiology 2019 19:84

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