Fig. 5
From: The gut microbiota facilitate their host tolerance to extreme temperatures
Cold and heat microbiota-transplanted mice altered intestinal morphology. (a) Representative images of the cecum, small intestine, and colon of RT, Cold and Heat mice. (b) H&E staining of duodenum of RT, Cold and Heat mice. Scale bars: 500 μm. (c) Small intestine lengths of 60 days RT, Cold and Heat mice. n = 6. (d) Small intestine widths of 60 days RT, Cold and Heat mice. n = 6. (e) Average microvilli lengths of RT, Cold and Heat mice. (f) Small intestine lengths of 60 days RT, Cold and Heat microbiota-transplanted mice. n = 6. (g) Small intestine widths of 60 days RT, Cold and Heat microbiota-transplanted mice. n = 6. (h) Average microvilli lengths of RT, Cold and Heat microbiota -transplanted mice. n = 6. The blue is at cold exposure (-5°C), and the red is at heat exposure (35°C). All values show mean ± SEM. Significance was calculated using non-paired two-tailed Student’s t test and one-way ANOVA followed by Tukey’s multiple comparisons test. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001