Fig. 1From: The gut microbiota facilitate their host tolerance to extreme temperaturesTemperature is a critical factor for body temperature maintenance and energy harvest. (a) The rectal temperature of mice after 4 and 8 h of room temperature (RT), cold temperature (Cold) and heat temperature (Heat). n = 8. (b) Changes in rectal temperature compared to initial as in (a). (c) Changes in body weight (compared to initial body weight) following RT, Cold and Heat. n = 8. (d) Food intake by mice was raised at RT, Cold and Heat. n = 8. They dramatically changed at the beginning of treatment, but gradually adapted to new stimuli. We only showed the results of the first 9 day in the Fig. 1c, d. (e-f) Hematoxylin-eosin (H&E) staining on paraffin sections from intSAT (e) and ingSAT (f) of RT, Cold and Heat mice. Cell size profiling of adipocytes from intSAT (e) and ingSAT (f) after 60 days of RT, Cold and Heat mice. The values show % from the total number of analyzed cells. Scale bars: 50 μm. All values show mean ± SEM. Significance was calculated using one-way ANOVA followed by Tukey’s multiple comparisons test. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001Back to article page