Table 2 Summary of differential gene expression analysis and enriched GO terms. The total number of differentially expressed genes (DEGs) identified across various comparisons were shown. The differential expressed genes were established using a significance threshold of FDR-adjusted p-values along with log2 fold change criteria. Additionally, the table includes the number of significantly enriched Gene Ontology (GO) terms for each comparison
From: Transcriptomic meta-analysis to identify potential antifungal targets in Candida albicans
Study | Condition 1 | Condition 2 | No. of DEGs | No. of up regulated genes | No. of down regulated genes | No. of significantly enriched GO terms |
|---|---|---|---|---|---|---|
[79] | ⍺-Ketoglutarate | Glucose | 1363 | 862 | 501 | 70 |
Casamino_acid | Glucose | 1413 | 843 | 570 | 97 | |
Glutamate | Glucose | 1495 | 960 | 535 | 73 | |
[83] | sfl2Δ_air | WT_air | 518 | 336 | 182 | 0 |
WT_CO2 | WT_air | 117 | 29 | 88 | 4 | |
sfl2Δ_CO2 | WT_CO2 | 767 | 510 | 257 | 27 | |
sfl2Δ_CO2 | sfl2Δ_air | 6 | 3 | 3 | 0 | |
[81] | GlcNAc-24 h | GlcNAc-5 h | 711 | 340 | 371 | 243 |
[82] | FBS_liquid | solid | 699 | 337 | 362 | 195 |
Lees_liquid | solid | 1474 | 793 | 681 | 232 | |
RMPI_liquid | solid | 594 | 244 | 350 | 93 | |
YPD_liquid | solid | 164 | 49 | 115 | 14 | |
Spider_liquid | solid | 256 | 213 | 43 | 46 | |
[80] | rtt109 Δ _Treated | rtt109 Δ _Untreated | 1331 | 691 | 640 | 333 |
cac2Δ Δ _Treated | cac2Δ_Untreated | 1845 | 941 | 904 | 352 | |
hat1Δ_Treated | hat1Δ_Untreated | 1412 | 728 | 684 | 326 | |
rtt109 Δ _Treated | WT_Treated | 1201 | 711 | 490 | 131 | |
cac2Δ_Treated | WT_Treated | 951 | 655 | 296 | 159 | |
hat1Δ_Treated | WT_Treated | 1406 | 988 | 418 | 127 | |
rtt109_Untreated | WT_Untreated | 375 | 330 | 45 | 23 | |
cac2Δ_Untreated | WT_Untreated | 527 | 507 | 20 | 9 | |
hat1Δ_Untreated | WT_Untreated | 1037 | 800 | 237 | 96 | |
WT_Treated | WT_Untreated | 3061 | 1561 | 1500 | 357 | |
[77] | mig1Δ_YPD_Acetic acid | mig1Δ_YPD_Untreated | 2229 | 1301 | 928 | 193 |
mig1Δ_YPD_Acetic acid | WT_YPD_Acetic acid | 1254 | 874 | 380 | 83 | |
mig1Δ_YPD_Butyric acid | mig1Δ_YPD_Untreated | 1066 | 628 | 438 | 70 | |
mig1Δ_YPD_Butyric acid | WT_YPD_Butyric acid | 117 | 105 | 12 | 7 | |
mig1Δ_YPD_Untreated | WT_YPD_Untreated | 178 | 127 | 51 | 4 | |
mig1Δ_YPM_Acetic acid | mig1Δ_YPM_Untreated | 2481 | 1428 | 1053 | 228 | |
mig1Δ_YPM_Acetic acid | WT_YPM_Acetic acid | 398 | 350 | 48 | 31 | |
mig1Δ_YPM_Butyric acid | mig1Δ_YPM_Untreated | 2107 | 1099 | 1008 | 152 | |
mig1Δ_YPM_Butyric acid | WT_YPM_Butyric acid | 28 | 14 | 14 | 3 | |
mig1Δ_YPM_Untreated | WT_YPM_Untreated | 87 | 56 | 31 | 0 | |
WT_YPD_Acetic acid | WT_YPD_Untreated | 1385 | 815 | 570 | 347 | |
WT_YPD_Butyric acid | WT_YPD_Untreated | 974 | 584 | 390 | 308 | |
WT_YPM_Acetic acid | WT_YPM_Untreated | 2640 | 1409 | 1231 | 189 | |
WT_YPM_Butyric acid | WT_YPM_Untreated | 2636 | 1404 | 1232 | 193 | |
[78] | Acetic acid_T1 | Untreated_T1 | 0 | 0 | 0 | 0 |
Acetic acid_T2 | Untreated_T2 | 0 | 0 | 0 | 0 | |
Acetic acid_T3 | Untreated_T3 | 155 | 3 | 152 | 15 | |
Acetic acid_T4 | Untreated_T4 | 0 | 0 | 0 | 0 | |
Butyric acid_T1 | Untreated_T1 | 0 | 0 | 0 | 0 | |
Butyric acid_T2 | Untreated_T2 | 0 | 0 | 0 | 0 | |
Butyric acid_T3 | Untreated_T3 | 1644 | 578 | 1066 | 177 | |
Butyric acid_T4 | Untreated_T4 | 0 | 0 | 0 | 0 | |
HCl_T1 | Untreated_T1 | 0 | 0 | 0 | 0 | |
HCl_T2 | Untreated_T2 | 381 | 363 | 18 | 7 | |
HCl_T3 | Untreated_T3 | 97 | 6 | 91 | 39 | |
HCl_T4 | Untreated_T4 | 0 | 0 | 0 | 0 | |
Lactic acid_T1 | Untreated_T1 | 106 | 106 | 0 | 0 | |
Lactic acid_T2 | Untreated_T2 | 0 | 0 | 0 | 0 | |
Lactic acid_T3 | Untreated_T3 | 52 | 2 | 50 | 15 | |
Lactic acid_T4 | Untreated_T4 | 0 | 0 | 0 | 0 | |
Propionic acid_T1 | Untreated_T1 | 3 | 3 | 0 | 1 | |
Propionic acid_T2 | Untreated_T2 | 0 | 0 | 0 | 0 | |
Propionic acid_T3 | Untreated_T3 | 22 | 3 | 19 | 0 | |
Propionic acid_T4 | Untreated_T4 | 0 | 0 | 0 | 0 |