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Table 2 Imipenem MIC Fold change after treatment with Efflux Pump Inhibitors against clinical CRAB strains

From: Regulation of overexpressed efflux pump encoding genes by cinnamon oil and trimethoprim to abolish carbapenem-resistant Acinetobacter baumannii clinical strains

Treatments

No. (%) of CRAB strains

≥ 2-fold

≥ 4-fold

≥ 6-fold

aIMP+TMPb (n=37)

35 (94.5)

4 (10.8)

-

IMP+OMPc (n=37)

31 (83.7)

4 (10.8)

-

IMP+CCCP (n=37)

8 (21.6)

-

-

IMP+Cinnamon (n=37)

34 (91.8)

15 (40.5)

1 (2.7)

IMP+Thyme (n=20)

13 (65)

2 (10)

-

IMP+Clove (n=20)

16 (80)

-

-

IMP+Carraway (n=20)

10 (50)

-

-

  1. aIMP Imipenem, bTMP Trimethoprim, cOMP Omeprazole