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Fig. 2 | BMC Microbiology

Fig. 2

From: Regulation of overexpressed efflux pump encoding genes by cinnamon oil and trimethoprim to abolish carbapenem-resistant Acinetobacter baumannii clinical strains

Fig. 2

Effect of treatment with EPI combined with IMP against two CRAb study strains (strains ACN15, and ACN99), where, (a, b): synergistic activity between IMP and cinnamene oil against CRAB isolates by checkerboard assay, Dark color represent higher density, and (c, d): bactericidal assays using imipenem combined with trimethoprim and cinnamon oil. y axis, log10 CFU/ml; x axis, time in hours; 2a, CRAB strain ACN15, 2b, CRAB strain CAN 99, black line: control strain without treatment, red: Imipenem alone at 16mg/L MIC; blue line: cinnamon oil alone at 0.5% (v/v), yellow line: Imipenem plus cinnamon oil at 2 mg/L/0.31% (v/v); green line; trimethoprim alone at 25 m g/L; violet line: synergy assay using imipenem plus trimethoprim at 2 mg/L/7.5mg/L

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