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Fig. 11 | BMC Microbiology

Fig. 11

From: Bioprocessing of Epothilone B from Aspergillus fumigatus under solid state fermentation: Antiproliferative activity, tubulin polymerization and cell cycle analysis

Fig. 11

Wound healing assay of the HepG2 cells in response to purified Epothilone from A. fumigatus comparing to the untreated cell lines (negative control) and treated with doxorubicin as positive control. After 24 h of growth of MCF-7 as homogenous monolayer, a scratch was made, and the extracted Epothilone was added (IC50 values 3.5 μg/ml), as well as, doxorubicin was added (IC50 values 2.4 μg/ml) to the medium, then the wound healing was measured at zero time after 24 h of incubation (A). The percentage of wound healing of the MCF7 cells in response to Epothilone from A. fumigatus was calculated (B)

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BMC Microbiology

ISSN: 1471-2180

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