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Table 6 Cytotoxic effects of biosynthesized SeNPs by Streptomyces parvulus MAR4 supernatant and Se/Ch-nanoconjugate against HePG-2 and Caki-1 (HTB-46) cell lines

From: Biogenic selenium nanoparticles and selenium/chitosan-Nanoconjugate biosynthesized by Streptomyces parvulus MAR4 with antimicrobial and anticancer potential

Tested NPs

HePG-2

In vitro Cytotoxicity, IC50 (μg/ ml) [a]

HTB-46

WI-38

SeNPs

13.04

21.35

85.69

Se/Ch-nanoconjugate

11.82

7.83

153.3

  1. [a]IC50 (μg): 1–5 (very strong); 6–15 (strong); 16–50 (moderate); 51–100 (weak), and > 100 (non-cytotoxic). Abbreviations: HepG2: Hepatocellular carcinoma cell line; Caki-1 (HTB-46): Renal cell carcinoma cell line; WI-38: Lung fibroblast cell lines