Fig. 4From: Targeted elimination of Vancomycin resistance gene vanA by CRISPR-Cas9 systemE. coli C600 containing the pCas9-sgRNA(20 bp) eliminated the vanA resistance genes. E. coliC600 + pUC19-vanA served as the donor, and E. coli C600 + pCas9-sgRNA(20 bp) or E. coli C600 + pCas9 served as the recipient strain. All bar graphs represent the mean of at least three biological replicates. Errors bars represent standard errors from three biological replicates. *p < 0.05Back to article page