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Fig. 3 | BMC Microbiology

Fig. 3

From: Multi-omics analysis of fecal microbiota transplantation’s impact on functional constipation and comorbid depression and anxiety

Fig. 3

Metabolic patterns before and after FMT in constipation patients with depression. (A) Analysis of orthogonal partial least-squares discriminant analysis (OPLS-DA) X-axis representation orthogonal signal correction (OSC) of the score of the main component of the process (t [1]P), Y-axis representation of the score of the OSC process (t [1]O). (B) Volcano plot of differential metabolites in the two groups. Blue dots represent downregulation, red dots represent upregulation, and gray indicates non-significant changes. (C) 5-HT levels in the two groups. (D) Pairwise comparison of 5-HT levels before and after FMT. (E) Receiver operating characteristic (ROC) curve of 5-HT in constipation patients with depression. (F) Bubble plot of metabolic pathways of differentially abundant metabolites in the two groups

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BMC Microbiology

ISSN: 1471-2180

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