Fig. 4From: Strontium ranelate enriched Ruminococcus albus in the gut microbiome of Sprague–Dawley rats with postmenopausal osteoporosisGut metabolites enriched in OVX_Sr group (a) and OVX group (b). Different row-side colors represent different super classes into which metabolites were classified. Different column-side colors represent different groups. cThe key stone species determined by a random forest classifier. d Spearman’s relationships between the key stone species and the metabolites. Each dot represents significant relationship (P < 0.05). The accumulation of four metabolites (e) in OVX_Sr increased with increased abundance of R. albus (f). Differences in metabolites between OVX and OVX_Sr groups (E) were calculated by using Wilcoxon rank sum testsBack to article page