Table 1 Clinical, epidemiological and molecular characteristics of Staphylococcus/Mammaliicoccus species recovered from DFUs and Healthy skin (n = 58)
Patient | Age/sex | PEDIS grade | Ulcer location | Antibiotics | Isolates (n) | Origin | species | SCCmec | ST-spa |
|---|---|---|---|---|---|---|---|---|---|
P01 | 73/M | 3 | Forefoot | Ciprofloxacin | 3 | DFU | S. aureus | IVd(2B) | ST672-t3841 |
| Â | Â | Â | Â | Â | Â | HS | S. aureus | IVd(2B) | ST672-t3841 |
| Â | Â | Â | Â | Â | Â | HS | S. epidermidis | MSCoNS | ST54 |
P02 | 51/F | 3 | Midfoot | Amoxicillin-clavulanate | 2 | HS | S. aureus | IVc(2B) | ST80-t1247 |
| Â | Â | Â | Â | Â | Â | HS | S. aureus | III(3Â A) | STNF-t037 |
P03 | 61/M | 4 | Heel | Metronidazole, Cefotaxime | 3 | DFU | S.aureus | IVc(2B) | ST80-t044 |
| Â | Â | Â | Â | Â | Â | HS | S.aureus | IVc(2B) | ST80-t044 |
|  |  |  |  |  |  | HS | S. haemolyticus | MSCoNS | ST3§ |
P04 | 62/M | 3 | Forefoot | Clindamycin, Ciprofloxacin | 2 | DFU | S. epidermidis | MSCoNS | ST54 |
| Â | Â | Â | Â | Â | Â | HS | S. epidermidis | MSCoNS | ST54 |
P05 | 60/F | 4 | Midfoot | Metronidazole, Cefotaxime | 3 | DFU | S. epidermidis | MSCoNS | ST54 |
| Â | Â | Â | Â | Â | Â | HS | S. haemolyticus | MSCoNS | ST29 |
| Â | Â | Â | Â | Â | Â | HS | M. sciuri | III(3Â A) | STNF |
P06 | 71/M | 3 | Forefoot | Ciprofloxacin | 2 | DFU | S. epidermidis | MSCoNS | ST54 |
| Â | Â | Â | Â | Â | Â | HS | S. epidermidis | MSCoNS | ST54 |
P07 | 61/M | 3 | Forefoot | Clindamycin | 1 | HS | S. epidermidis | MSCoNS | STNF |
P08 | 63/F | 3 | Heel | Metronidazole, Cefotaxime | 1 | HS | S. haemolyticus | MSCoNS | ST25 |
P09 | 64/M | 4 | Forefoot | Cefotaxime | 3 | DFU | S. aureus | IVc(2B) | ST80-t044 |
| Â | Â | Â | Â | Â | Â | DFU | S. caprae | MSCoNS | STNF |
| Â | Â | Â | Â | Â | Â | HS | S. aureus | IVc(2B) | ST80-t044 |
P10 | 73/M | 2 | Heel | Amoxicillin-clavulanate | 2 | DFU | S. aureus | MSSA | ST291-t937 |
| Â | Â | Â | Â | Â | Â | HS | S. hominis | MSCoNS | STNF |
P11 | 66/M | 2 | Midfoot | Clindamycin | 1 | DFU | S. aureus | III(3Â A) | STNF-t037 |
P13 | 54/M | 4 | Forefoot | Bactrim | 1 | HS | S. epidermidis | MSCoNS | ST35 |
P14 | 80/F | 2 | Forefoot | Imipenem | 1 | HS | S. haemolyticus | MSCoNS | ST3 |
P15 | 74/M | 2 | Heel | Amoxicillin-clavulanate | 3 | DFU | S. aureus | III(3Â A) | ST241-t037 |
| Â | Â | Â | Â | Â | Â | HS | S. aureus | III(3Â A) | ST241-t037 |
| Â | Â | Â | Â | Â | Â | HS | S. epidermidis | MSCoNS | ST35 |
P16 | 61/M | 3 | Forefoot | Cefazolin | 2 | DFU | S. aureus | III(3Â A) | ST241-t037 |
| Â | Â | Â | Â | Â | Â | HS | S. haemolyticus | MSCoNS | ST3 |
P17 | 70/M | 2 | Heel | Bactrim | 2 | DFU | S. epidermidis | MSCoNS | ST640 |
| Â | Â | Â | Â | Â | Â | HS | S. simulans | MSCoNS | STNF |
P18 | 49/M | 4 | Midfoot | Clindamycin, Cefotaxime | 1 | HS | S. simulans | MSCoNS | STNF |
P19 | 44/M | 3 | Forefoot | Imipenem | 2 | DFU | S. caprae | MSCoNS | STNF |
| Â | Â | Â | Â | Â | Â | HS | S. simulans | MSCoNS | STNF |
P20 | 71/M | 2 | Midfoot | Imipenem | 1 | HS | S. haemolyticus | MSCoNS | ST1 |
P26 | 85/M | 4 | Heel | Clindamycin, Ciprofloxacin | 1 | DFU | S. aureus | III(3Â A) | STNF-t037 |
P27 | 82/M | 4 | Forefoot | Metronidazole, Cefotaxime | 1 | HS | S. haemolyticus | MSCoNS | ST56 |
P28 | 72/M | 4 | Midfoot | Metronidazole, Cefotaxime | 1 | HS | S. haemolyticus | MSCoNS | ST25 |
P29 | 54/M | 3 | Heel | Bactrim, Cefotaxime | 1 | HS | S. aureus | IVc(2B) | ST80-t044 |
P30 | 59/M | 3 | Forefoot | Ciprofloxacin | 1 | HS | S. aureus | MSSA | ST97-t9432 |
P31 | 64/M | 4 | Forefoot | Clindamycin, Ciprofloxacin | 1 | DFU | S. aureus | IVd(2B) | ST672-t3841 |
P32 | 60/M | 3 | Heel | Metronidazole, Cefotaxime | 2 | DFU | S. aureus | III(3Â A) | ST241-t037 |
| Â | Â | Â | Â | Â | Â | HS | S. aureus | III(3Â A) | ST241-t037 |
S16* | 57/F | 3 | Heel | Cefazolin | 1 | DFU | S. aureus | MSSA | STNF-t037 |
S17K* | 72/M | 2 | Heel | Amoxicillin-clavulanate | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S104K* | 60/F | 2 | Midfoot | Imipenem | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S4K* | 59/M | 2 | Forefoot | Clindamycin, Ciprofloxacin | 1 | DFU | S. saprophyticus | MSCoNS | STNF |
S6K* | 49/M | 3 | Midfoot | Bactrim | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S7K* | 58/M | 3 | Heel | Ciprofloxacin | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S8K* | 60/M | 4 | Heel | Metronidazole, Cefotaxime | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S9K* | 52/M | 3 | Midfoot | Cephalexin, Gentamicin | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S10K* | 60/M | 4 | Forefoot | Metronidazole, Cefotaxime | 1 | DFU | S. aureus | IVc(2B) | ST80-t044 |
S11K* | 67/M | 4 | Heel | Clindamycin, Ciprofloxacin | 2 | DFU | S. aureus | IVc(2B) | ST80-t044 |
| Â | Â | Â | Forefoot | Â | Â | DFU | S. aureus | IVc(2B) | ST80-t044 |
S12K* | 85/M | 3 | Forefoot | Ciprofloxacin | 2 | DFU | S. aureus | IVc(2B) | ST80-t044 |
| Â | Â | Â | Heel | Â | Â | DFU | S. aureus | MSSA | ST1-t127 |
S14K* | 60/F | 4 | Midfoot | Cefazolin | 1 | DFU | S. aureus | MSSA | ST1-t127 |