Whole genome structure and resistance genes in carbapenemase-producing multidrug resistant ST378 Klebsiella pneumoniae

Table 1 Identified genome profiles from K. pneumoniae isolates

Bacterial Strain	Gene type (name)	Gene Length (bp)	GC contents	CDS	rRNA	tRNA
DMCPKP1	Chromosome	5,291,572	57.45	4,886	25	89
	Plasmid (pKP1_IncHI1B/IncFIB)	456,420	48.04	529	0	0
	Plasmid (pKP1gtc3L95)	95,047	52.4	111	0	0
	Plasmid (pKP1gtc5L70)	70,930	51.05	84	0	0
	Plasmid (pKP1-NDM5)	46,112	47.04	58	0	0
DMCPKP4	Chromosome	5,290,663	57.45	4,896	25	89
	Plasmid (pKP4_IncHI1B/IncFIB)	434,340	48.04	468	0	0
	Plasmid (pKP4gtc3L95)	95,046	52.4	107	0	0
	Plasmid (pKP4gtc4L70)	70,932	51.05	84	0	0
	Plasmid (pKP4-NDM5)	46,112	47.04	58	0	0

As a result of the sequencing and assembly, multiple gene components were identified. Each strain was identified to contain single chromosome and 4 plasmids, respectively. Six different types were discovered from four heterogenous plasmids. Three types (IncFIB(pNDM-Mar), IncHI1B(pNDM-MAR) and IncFIB(K)) of plasmids were discovered as integrated form in the pKP1_IncHI1B/IncFIB and pKP4_IncHI1B/IncFIB

ISSN: 1471-2180