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Table 4 Top ten cytoHubba-ranked genes from among the top-16 with respect to node degree

From: Sub-lethal concentration of a colloidal nanosilver formulation (SilversolĀ®) triggers dysregulation of iron homeostasis and nitrogen metabolism in multidrug resistant Pseudomonas aeruginosa

No.

Gene ID

Gene Name

Number of methods ranking this protein among top ten

Names of 12 ranking methods of CytoHubba and rank score provided by them

Degree

MNC

DMNC

MCC

Bottleneck

EcCentricity

Closeness

Radiality

Betweenness

Stress

CC

EPC

1

PA0520

nirQ

12

11

11

0.729

46,200

1

0.5

13

3

5.788

36

0.781

6.331

2

PA3392

nosZ

12

10

10

0.758

45,480

3

0.5

12.5

2.93

3.404

24

0.844

6.255

3

PA0519

nirS

10

14

14

-

46,344

7

0.5

14.5

3.2

34.704

124

-

6.928

4

PA0524

norB

10

13

13

0.638

46,320

-

0.5

14

3.13

18.621

92

-

6.827

5

PA0516

nirF

10

12

12

0.658

45,600

-

0.5

13.5

3.06

13.738

72

-

6.663

6

PA0521

Cyto.c

10

10

10

0.778

46,080

-

-

12.33

2.86

2.038

12

0.866

6.084

7

PA0525

norD

9

10

10

0.778

46,080

-

-

12.33

2.86

2.038

-

0.866

6.064

8

PA3877

narK1

9

9

9

-

-

2

0.5

12

2.86

15.750

82

-

5.714

9

PA0518

nirM

9

8

8

0.758

5760

1

0.33

11.33

2.73

-

-

0.928

-

10

PA3395

nosY

9

8

8

0.816

40,320

1

-

11.33

2.73

-

-

1

5.642

  1. ā€˜-ā€™indicates that the given method did not rank that particular gene among top ten