Fig. 4

Associations of cigarette smoking-related oral bacterial genera (A) and pathways (B) with cardiometabolic risk factors. The color of the heat map represents the T value of the relationship between microbial features and cardiometabolic risk factors (that is, the effect value obtained by the regression model divided by SD). * FDR q < 0.20, ** FDR q < 0.10. Regression models were adjusted for sex, age, education level, personal annual income, body mass index, alcohol drinking, tea drinking and daily tooth brushing frequency. TG, Triglyceride; CHOL, Cholesterol; HDL-C; High-density lipoprotein cholesterol; LDL-C, Low-density lipoprotein cholesterol; GLU, Glucose; CRP, C-reactive protein