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Table 1 FIC index for the combined activity of the phytochemicals with antibiotics against UPEC isolates

From: Repurposing carvacrol, cinnamaldehyde, and eugenol as potential anti-quorum sensing agents against uropathogenic Escherichia coli isolates in Alexandria, Egypt

 

FIC index

(Interpretation)

Carvacrol

+

Cinnamaldehyde

+

Eugenol

+

CIP

CTR

CL

DO

TGC

CIP

CTR

CL

DO

TGC

CIP

CTR

CL

DO

TGC

E18

1

(Add)

0.27

(Syn)

0.53

(PSyn)

0.56

(PSyn)

1

(Add)

1.25

(Ind)

0.75

(PSyn)

1.25

(Ind)

0.56

(PSyn)

0.75

(PSyn)

0.625

(PSyn)

0.75

(PSyn)

1.25

(Ind)

1.25

(Ind)

0.53

(PSyn)

E35

1

(Add)

0.75

(PSyn)

0.5

(Syn)

0.625

(PSyn)

1

(Add)

1

(Add)

1

(Add)

0.75

(PSyn)

1.25

(Ind)

1.25

(Ind)

0.75

(PSyn)

0.75

(PSyn)

1

(Add)

1

(Add)

0.5

(Syn)

E63

0.75

(PSyn)

0.625

(PSyn)

0.75

(PSyn)

0.75

(PSyn)

1.25

(Ind)

1.12

(Ind)

1

(Add)

1

(Add)

1

(Add)

0.625

(PSyn)

0.625

(PSyn)

0.5

(Syn)

0.75

(PSyn)

0.56

(PSyn)

0.75

(PSyn)

  1. CIP: ciprofloxacin, CTR: ceftriaxone, CL: colistin, DO: doxycycline, TGC: tigecycline. Ind, Add, PSyn, and Syn indicate indifference, additive effect, partial synergy, and synergy, respectively
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BMC Microbiology

ISSN: 1471-2180

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