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Table 2 Detectable pathogen count by mNGS and culture methods

From: Composition of pathogenic microorganism in chronic osteomyelitis based on metagenomic sequencing and its application value in etiological diagnosis

Types of Pathogenic Microorganisms

mNGS

culture

P

Total

68%

56%

0.07

Aerobic and facultative anaerobes

54%

50%

0.625

Anaerobe and MTB

18%

4%

<0.05

Mixed infection

22%

10%

<0.05