Table 3 Effects of antibiotic combinations on 10 K. pneumoniae strains in planktonic state

K.1

0.12/2

0.37 (S)

0.25/(256/128)

0.75 (I)

8/(512/256)

1.00 (I)

4/0.5

1.13 (I)

16/2

0.63 (I)

4/(128/64)

0.25 (S)

K.2

0.5/4

0.75 (I)

0.25/(64/32)

0.38 (S)

4/(512/256)

0.75 (I)

512/0.03

0.53 (I)

64/8

0.56 (I)

512/(256/128)

0.75 (I)

K.3

0.12/4

0.19 (S)

0.5/(64/32)

0.38 (S)

1/(256/128)

0.28 (S)

64/0.06

0.28 (S)

128/16

1.00 (I)

64/(512/256)

0.75 (I)

K.4

0.25/16

0.50 (S)

0.12/(8/4)

0.25 (S)

16/(2/1)

0.28 (S)

4/0.12

0.38 (S)

2/8

0.25 (S)

8/(8/4)

0.63 (I)

K.5

0.5/4

0.27 (S)

1/(256/128)

0.63 (I)

64/(256/128)

0.38 (S)

32/1

0.53 (I)

1024/128

1.50 (I)

256/(128/64)

0.31 (S)

K.6

1/0.5

0.38 (S)

1/(128/64)

0.50 (S)

1/(64/32)

0.38 (S)

4/0.5

0.63 (I)

1/0.5

0.25 (S)

2/(128/64)

0.50 (S)

K.7

16/16

1.50 (I)

8/(32/16)

0.28 (S)

8/(256/128)

0.75 (I)

16/16

0.75 (I)

4/4

0.31 (S)

1/(256/128)

0.27 (S)

K.8

8/16

0.75 (I)

4/(64/32)

0.16 (S)

4/(512/256)

0.38 (S)

32/16

0.75 (I)

64/8

0.75 (I)

64/(512/256)

0.75 (I)

K.9

1/4

0.16 (S)

16/(16/8)

0.53 (I)

4/(128/64)

0.38 (S)

2/16

0.56 (I)

16/4

0.75 (I)

0.25/(128/64)

0.26 (S)

K.10

4/32

0.38 (S)

2/(1024/512)

0.50 (S)

16/(512/256)

0.19 (S)

32/4

0.38 (S)

32/32

0.25 (S)

32/(1024/512)

0.38 (S)