Group | 0.5 h | 2 h | 4 h | 12 h |
---|
Control | 0 | 0 | 0 | 0 |
SV | 10.21 ± 1.79 | 3.32 ± 0.58 | 0.48 ± 0.03 | # |
VP | 2.68 ± 0.32 | 0.71 ± 0.08 | 0.50 ± 0.04 | # |
SV&VP | 14.14 ± 1.18 | 7.49 ± 0.62 | 1.40 ± 0.23 | # |
- Control (no antibiotics); SV Systemic vancomycin (intraperitoneal injection, 88 mg/kg, every 12 h), VP Intra-wound vancomycin powder (before closure of the capsule, 88 mg/kg, single dosage), SV&VP Systemic vancomycin & intra-wound VP (intraperitoneal injection, 88 mg/kg, every 12 h; combined with intra-wound VP before closure of the capsule, 88 mg/kg, single dosage). n = 6. # Below the limit of detection (0.1 μg/ml)