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Fig. 7 | BMC Microbiology

Fig. 7

From: Candida albicans and Candida glabrata triosephosphate isomerase – a moonlighting protein that can be exposed on the candidal cell surface and bind to human extracellular matrix proteins

Fig. 7

Wall-eyed stereo view of a model for the interaction between C. albicans Tpi1 and VTR. The indicated dimer of C. albicans Tpi1 (purple), with an active site denoted in gray, was obtained by homology modeling with Modeller software, based on the S. cerevisiae Tpi structure (66 % identity; PDB, 3 ypi). Tpi1 amino acids, marked in yellow, are directly involved in the interaction with VTR (green), as found by chemical cross-linking. An additional movie file shows this interaction in more detail (see Supplementary material Video S1)

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BMC Microbiology

ISSN: 1471-2180

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