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Table 6 Allele and genotype frequencies of IL1B-31 polymorphism among H. pylori infected and uninfected subjects, and their contributions to H. pylori infection

From: First insights into the molecular basis association between promoter polymorphisms of the IL1B gene and Helicobacter pylori infection in the Sudanese population: computational approach

 

H. pylori (+ve)

n = 61

H. pylori (−ve)

n = 61

OR (95% CI)*

Allele frequency

 IL1B-31-C

77 (63.11%)

93 (76.23%)

0.5336 (0.3060–0.9304)

 IL1B-31-T

45 (36.89%)

29 (23.77%)

 P-value

0.0363

 

Genotype frequency

 C/C

28 (45.90%)

40 (65.57%)

1 (reference)

 T/C

21 (34.41%)

13 (21.31%)

0.4333 (0.1864–1.008)

 T/T

12 (19.67%)

8 (13.12%)

0.4667 (0.1688–1.290)

 T/C + T/T

33 (54.1%)

21 (34.43%)

0.4455 (0.2147–0.9243)

 P-value

0.0445

 
  1. *OR, odds ratio; 95%CI, 95% confidence interval