Table 1 Bacterial load (log10 CFU/swab) after treatments in diabetic mice wounds infected with MDR S. aureus
Mouse ID | Treatment group | Infection period | ||||
|---|---|---|---|---|---|---|
Day 0 | Day 3 | Day 5 | Day 7 | Day 10 | ||
4-NEM | Saline | 0 | 8.99 | 8.36 | 8.51 | 8.57 |
4-1 L | 0 | 7.72 | 8.11 | 8.43 | 7.91 | |
4-2R | 0 | 8.34 | 8.85 | 8.38 | 8.18 | |
5-NEM | 0 | 7.00 | 8.34 | 8.41 | 7.62 | |
5-1 L | 0 | 8.76 | 8.70 | 8.20 | 8.11 | |
5-2R | 0 | 6.97 | 7.73 | 8.51 | 8.53 | |
10-RL | 0 | 7.00 | 8.38 | 8.26 | 7.95 | |
Mean + err | 0 | 8.42 + 0.9 | 8.47 + 0.4 | 8.39 + 0.1 | 8.23 + 0.3 | |
7-1R | Phage | 0 | 8.40 | 6.43 | 2.26 | 0.00 |
7-1 L | 0 | 8.40 | 6.18 | 5.72 | 2.00 | |
7-RL | 0 | 7.88 | 6.45 | 6.30 | 2.28 | |
7-2R | 0 | 8.56 | 6.26 | 6.63 | 0.00 | |
9-NEM | 1.1 | 8.38 | 6.28 | 2.48 | 4.34 | |
9-1R | 1.5 | 8.81 | 6.45 | 5.15 | 0.00 | |
9-1 L | 0 | 8.41 | 5.80 | 5.72 | 0.00 | |
9-RL | 0 | 6.66 | 5.43 | 2.32 | 0.00 | |
Mean + err | 0.3 | 8.19 + 0.7 | 6.16 + 0.4 | 4.57 + 1.9 | 1.08 + 1.6 | |
6-1R | Vancomycin | 0 | 8.64 | 6.18 | 5.15 | 7.04 |
6-RL | 0 | 7.46 | 4.70 | 3.96 | 5.86 | |
6-2R | 0 | 8.04 | 7.99 | 4.75 | 6.75 | |
8-NEM | 0 | 7.84 | 6.49 | 5.58 | 1.04 | |
8-1 L | 0 | 7.80 | 6.52 | 4.28 | 6.04 | |
8-2R | 0 | 7.72 | 7.92 | 4.96 | 2.11 | |
Mean + err | 0 | 7.92 + 0.4 | 6.63 + 1.2 | 4.78 + 0.6 | 4.81 + 2.6 | |