Table 1 MICs of first-line TB drugs in M. smegmatis transformants
From: LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate
Drug | Minimum inhibitory concentration (MIC) | |
|---|---|---|
M. smegmatis pMV261 | M. smegmatis pMV261-LipF | |
Rifampicin | 3.12 μg/mL | 1.6 μg/mL |
Isoniazid | 32.0 μg/mL | 32.0 μg/mL |
Ethambutol | 0.5 μg/mL | 0.5 μg/mL |
Pyrazinamide | > 200 μg/mL | > 200 μg/mL |
Streptomycin | 0.25 μg/mL | 0.06 μg/mL |