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Fig. 4 | BMC Microbiology

Fig. 4

From: Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes

Fig. 4

MD suppressed the transcription of viral genes. a-c L929 was pretreated with DMSO or MD (3.0 μM) for 1 h prior to HSV-1 infection for additional 2 h. The expression levels of indicated genes were measured by quantitative PCR. The 293 T cells were transfected with the vector and ICP0 promoter after treated with DMSO and MD (1 μM) for 1 h. Cells were harvested to determine luciferase activity 36 h post transfection (d)

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BMC Microbiology

ISSN: 1471-2180

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