No.a | Coveragea | Peak position | DNA microarray 13032ΔftsR/13032 | Potential FtsR target genes | ||||
---|---|---|---|---|---|---|---|---|
in gene | downstream 3′-end of | upstream of | Gene | mRNA ratio | p-value | |||
1 (1) | 28,811 (4781) | – | cg2478 (NCgl2178, penicillin binding protein) ← | cg2477 (NCgl2177, conserved hypothetical protein) ← | cg2478 | 0.75 | 0.11 | cg2477 potentially activated by FtsR |
cg2477 | 0.24 | 0.01 | ||||||
2 (5) | 22,757 (934) | – | – | cg3182 (NCgl2777, cop1, trehalose corynemycolyl transferase) ← | cg3182 | 1.70 | 0.20 | cop1-cg3181-cg3180 potentially repressed by FtsR |
cg3181 | 2.30 | 0.05 | ||||||
cg3180 | 1.91 | 0.05 | ||||||
cg3181 (NCgl2776, put. Secreted protein) ← cg3180 (NCgl2775, put. Secreted protein) ← cg3183 (NCgl2778, put. transposase) → | cg3183 | n.a. | n.a. | |||||
3 (2) | 4437 (1556) | – | cg2367 (NCgl2076, ftsQ, cell division septal protein) ← | cg2366 (NCgl2075, ftsZ, cell division GTPase) ← | cg2367 | 1.20 | 0.02 | ftsZ activated by FtsR |
cg2366 | 0.35 | 0.02 | ||||||
4 (11) | 3899 (373) | cg0470 (NCgl0381, htaB, heme transport-associated protein) → | cg0469 (NCgl0380, hmuV) → | cg0471 (NCgl0382, htaC, heme-transport associated protein) → | cg0469 | 1.41 | < 0.01 | – |
cg0470 | 1.45 | 0.09 | ||||||
cg0471 | 1.55 | 0.03 | ||||||
5 (12) | 3836 (365) | – | – | cg0852 (NCgl0712, conserv. Hypoth. protein) ← | cg0852 | 0.62 | 0.01 | cg0852 potentially activated by FtsR |
cg0853 (NCgl0713, conserv. Hypoth. protein) → cg0854 (NCgl0714, pmmA, phosphomannomutase) → cg0855 (NCgl0715, conserv. Hypoth. protein) → cg0856 (NCgl0716, mannose-6-phosphate isomerase) → | cg0853 | 1.03 | 0.29 | |||||
cg0854 | 0.89 | 0.25 | ||||||
cg0855 | 1.18 | 0.08 | ||||||
cg0856 | 1.09 | 0.03 | ||||||
6 (3) | 3630 (1529) | – | cg3392 (oxiE, idhA2, NCgl2958) → (myo-inositol 2-dehydrogenase) | cg3393 (NCgl2959, phoC, secreted cell-wall-associated phosphatase) → | cg3392 | 1.25 | 0.03 | phoC potentially repressed by FtsR |
cg3393 | 1.60 | 0.03 | ||||||
7 (15) | 2871 (315) | cg2695 (NCgl2368, ATPase of ABC transporter) ← | cg2697 (ssb, NCgl2370, single-strand DNA-binding protein) ← | cg2694 (NCgl2367, put. Phosphodiesterase, nucleotide pyrophosphatase) ← cg2693 (NCgl2366, put. Phosphodiesterase, nucleotide pyrophosphatase) ← | cg2693 | 1.31 | 0.03 | – |
cg2694 | 1.29 | 0.05 | ||||||
cg2695 | 1.06 | 0.42 | ||||||
cg2697 | 1.04 | 0.24 | ||||||
8 (6) | 2355 (858) | – | cg2518 (NCgl2213, put. Secreted protein) → cg2519 (NCgl2214, conserv. Hypoth. protein) ← cg2520 (NCgl2215, hypoth. protein) ← cg2521 (NCgl2216, fadD15, long chain fatty acid CoA ligase) ← | – | cg2518 | 0.81 | 0.18 | – |
cg2519 | 0.49 | 0.03 | ||||||
cg2520 | 0.92 | 0.45 | ||||||
cg2521 | 0.91 | 0.43 | ||||||
9 (8) | 2248 | cg0839 (NCgl0701) ← (hypoth. protein) | cg0840 (NCgl0702, conserv. Hypoth. protein) ← | cg0838 (NCgl0700, ATP-depend. helicase) ← | cg0838 | 4.61 | 0.03 | cg0838 potentially repressed |
cg0839 | 2.45 | 0.16 | by FtsR | |||||
cg0840 | 2.45 | 0.19 |