Skip to main content

Table 1 Patients’ characteristics

From: Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery

 

Non-complicated

Medical complication

Surgical complication

All complications

p-value non-comp. vs. med. Comp.

p-value non-comp. vs. surg. Comp.

p-value non-comp. vs. all comp.

Number

15

51

141

17

 

Age [years]

59.0 (50.0–63.5)

75.0 (75.0–75.0)

68.5 (63.3–74.0)

69.0 (62–75)

0.013*

0.009**

0.002**

ASA status

2.0 (2.0–2.0)

2.0 (2.0–3.0)

3.0 (2.0–3.0)

3.0 (2.0–3.0)

0.327

0.014*

0.021*

Cardiovascular risk factors

 Coronary heart disease

2 (13.3%)

1 (20.0%)

1 (7.1%)

1 (5.9%)

0.718

0.584

0.801

 Diabetes

3 (20.0%)

2 (40.0%)

4 (28.6%)

5 (29.4%)

0.371

0.590

0.447

 Arterial hypertension

5 (33.3%)

4 (80.0%)

6 (42.9%)

8 (47.1%)

0.069

0.597

0.260

 Chronic renal failure

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000

1.000

1.000

Primary disease

 Malignant

8 (53.3%)

4 (80.0%)

8 (57.1%)

11 (64.7%)

0.292

0.837

0.563

 IPMN

2 (12.5%)

1 (20.0%)

6 (42.9%)

6 (35.3%)

0.718

0.075

0.123

 Chronic pancreatitis

5 (33.3%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0.136

0.018*

0.006**

Operation

 Partial pancreaticoduodenectomy

3 (20.0%)

1 (20.0%)

3 (21.4%)

4 (23.5%)

1.000

0.924

0.940

 Pylorus-preserving pancreas head resection

5 (33.3%)

3 (60.0%)

5 (35.7%)

6 (35.3%)

0.292

0.893

0.601

 Total pancreatectomy

2 (13.3%)

1 (20.0%)

0 (0.0%)

1 (5.9%)

0.718

0.157

0.410

 Distal pancreatectomy

3 (20.0%)

0 (0.0%)

3 (21.4%)

3 (17.7%)

0.278

0.924

0.749

 Tumour enucleation

2 (13.3%)

0 (0.0%)

3 (21.4%)

3 (17.7%)

0.389

0.564

0.841

 Surgery [min]

285.0 (187.5–345.0)

240.0 (240.0–330.0)

217.5 (153.8–337.5)

240.0 (165.0–330.0)

0.726

0.444

0.639

 Blood loss2 [mL]

750.0 (500.0–1150.0)

700.0 (600.0–800.0)

600.0 (500.0–700.0)

600.0 (500.0–800.0)

0.965

0.273

0.393

 Infusion2 [mL]

3500.0 (2500.0–4250.0)

3000.0 (3000.0–4500.0)

2750.0 (2000.0–3375.0)

3000.0 (2000.0–3500.0)

0.756

0.186

0.352

 Transfusion2 [mL]

0.0 (0.0%)

0.0 (0.0%)

0.0 (0.0%)

0.0 (0.0%)

1.000

1.000

1.000

 CRP3 [mg/L]

56.2 (36.4–114.8)

135.6 (79.9–151.9)

114.0 (76.9–160.7)

103.9 (74.4–153.0)

0.020*

0.004**

0.001**

 Leucocytes3 [1/nL]

9.0 (7.9–10.3)

11.4 (9.0–17.4)

11.7 (76.9–160.9)

11.4 (8.3–14.0)

0.015*

0.025*

0.007**

Hospital stay

 In total [days]

10.0 (9.0–11.5)

21.0 (13.0–45.0)

27.0 (15.0–44.5)

21.0 (13.0–43.0)

0.007**

0.001**

< 0.001***

 Intermediate care unit [days]

0.0 (0.0–0.0)

5.0 (0.0–23.0)

0.0 (0.0–4.8)

0.0 (0.0–5.0)

0.041*

0.245

0.095

 Intensive care unit [days]

0.0 (0.0–0.0)

1.0 (0.0–1.0)

0.0 (0.0–1.0)

0.0 (0.0–1.0)

0.033*

0.059

0.027*

Postoperative complications [Clavien-Dindo classification]

 Grade I

0 (0.0%)

0 (0.0%)

4 (28.6%)

4 (23.5%)

1.000

0.026*

0.059

 Grade II

0 (0.0%)

3 (60.0%)

3 (21.4%)

6 (35.3%)

0.001**

0.058

0.016*

 Grade III4

0 (0.0%)

0 (0.0%)

6 (42.9%)

6 (35.3%)

1.000

0.004**

0.016*

 Grade IV5

0 (0.0%)

2 (40.0%)

1 (7.1%)

2 (11.8%)

0.010*

0.129

0.059

 Grade V

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1.000

1.000

1.000

  1. Data are presented as the median and interquartile range (Q1–Q3) or as count and percentage. A p-value < 0.05 was considered statistically significant and are highlighted in boldface. Concerning symbolism and higher orders of significance: p < 0.05 *, p < 0.01 **, p < 0.001 ***. ASA status, American Society of Anesthesiologists physical status classification system; IPMN, intraductal papillary mucinous neoplasm; CRP, C-reactive protein. 1Two patients suffered from medical and surgical complications, therefore both have been allocated into the medical as well as the surgical complication group; 2total measured intraoperatively; 3postoperative observation period; 4includes grades IIIa and IIIb; 5 includes grades IVa and IVb
Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us