Table 5 Cytotoxicity IC50 values of different organic extracts of C. nigricolor on HeLa and MCF-7 cells
From: Diversity and biological activities of endophytic fungi associated with Catharanthus roseus
Extracts of C. nigricolor under study | Cytotoxic activity IC 50 (μg mL−1) | |
|---|---|---|
HeLa | MCF-7 | |
EA mycelial extract | 25 ± 0.4 | >  100 |
EA culture filtrate extract | 50 ± 0.02 | >  100 |
Chloroform mycelial extract | >  100 | >  100 |
Chloroform culture filtrate extract | >  100 | >  100 |
Dichloromethane mycelial extract | >  100 | >  100 |
Dichloromethane culture filtrate extract | >  100 | >  100 |
Hexane mycelial extract | >  100 | >  100 |
Hexane culture filtrate extract | >  100 | 45 ± 0.04 |
+ ve control | Vincristine | 1.2 |