Fig. 2

The Web of Microbes datacube and metabolic interaction web. Data on the WoM is sliced into two-dimensional views. For the control (“The Environment”), metabolites are “present” (tan) or “not detected” (gray). In the metabolically transformed environments (indicated by organism name), metabolites are coded as “decreased” (blue), “increased” (red) or “not changed” (white). Data constrained by selection of an environment can also be viewed in the form of a web. The size of each circle (metabolite) in the center of the web is relative to the number of organisms interacting with the metabolite. Filled circles indicate the metabolite was detected in the control exometabolite pool. Hollow circles indicate products not detected in the control environment. Connecting lines indicate metabolite increases (red) or decreases (blue) in the transformed metabolite pool