Comparison of biomarker based Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and conventional methods in the identification of clinically relevant bacteria and yeast

Table 4 Comparison of the sensitivities of Vitek 2 and MALDI-TOF MS in the identification of selected yeast to the species and genus levels

Organism (n)	Number (%) of isolates with Correct identification to the species level:			Number (%) of isolates with Correct identification to the genus level:
Organism (n)	Vitek	MALDI-TOF MS	P value	Vitek	MALDI-TOF MS	P value
Candida albicans (5)	5	5		5	5
Candida dubliniensis (2)	2	2		2	2
Candida glabrata (4)	4	4		4	4
Candida guillermondii (1)^a	-	-		-	-
Candida haemulonii (6)^a	-	-		-	-
Candida kefyr (1)	1	1		1	1
Candida krusei (4)	4	4		4	4
Candida parapsilosis (2)	2	2		2	2
Candida tropicalis (4)	3	4	0.285	4	4
Cryptococcus neoformans (1)	1	1		1	1
Total (23)	22 (95.7)	23 (100.0)	0.312	23 (100.0)	23 (100.0)

KEY: ^a6 isolates of Candida haemulonii and 1 isolate of Candida guillermondii have been excluded from analysis as they were not identified by MALDI-TOF MS.

ISSN: 1471-2180