Diversity, Phylogeny, anticancer and antimicrobial potential of fungal endophytes associated with Monarda citriodora L.

Table 4 Anticancer activity of the extracts (100 μg mL⁻¹) prepared from endophytic fungi isolated from M. citriodora

	Tissue		Lung	Colon	Breast	Prostate
S.No.	Cell line type		A549	HCT116	MCF7	PC-3
	Code	Conc (μg mL⁻¹)	Percent Growth inhibition
1	MC-1 L	100	13 ± 0.8	0 ± 0	13 ± 0.3	16 ± 0.5
2	MC-2 L	100	35 ± 1	22 ± 0.3	52 ± 0	10 ± 0
3	MC-3 L	100	33 ± 0.5	12 ± 0.4	20 ± 0.4	41 ± 0.4
4	MC-4 L***	100	67 ± 1	65 ± 0.2	91 ± 0.2	79 ± 0.3
5	MC-5 L	100	0 ± 0	47 ± 0	76 ± 0	51 ± 0.4
6	MC-6 L	100	27 ± 0.5	35 ± 0.5	54 ± 0.5	56 ± 0.4
7	MC-8 L***	100	98 ± 1	99 ± 0.4	94 ± 0.4	95 ± 0.4
8	MC-9 L	100	22 ± 0.8	10 ± 0.2	14 ± 0.3	48 ± 0.2
9	MC-10 L	100	47 ± 0	18 ± 0.4	45 ± 0.4	49 ± 0
10	MC-12 L	100	34 ± 1	29 ± 0.6	37 ± 0.2	58 ± 0
11	MC-14 L***	100	96 ± 1	100 ± 0.2	94 ± 0.3	100 ± 0.2
12	MC-15 L	100	24 ± 0.8	51 ± 0.8	86 ± 0	59 ± 0.5
13	MC-16 L***	100	59 ± 0	47 ± 0.2	88 ± 0.2	61 ± 0.2
14	MC-17 L	100	48 ± 1	23 ± 0	23 ± 0.5	25 ± 0
15	MC-18 L***	100	100 ± 0	93 ± 0.5	100 ± 0.2	90 ± 0.2
16	MC-20 L***	100	77 ± 1	82 ± 0.5	77 ± 0.2	63 ± 0.5
17	MC-24 L***	100	77 ± 1	99 ± 0.4	88 ± 0.4	96 ± 0
18	MC-25 L***	100	88 ± 1	100 ± 0.2	94 ± 0.3	99 ± 0.4
19	MC-13R	100	40 ± 1	20 ± 0.6	35 ± 0.2	50 ± 0.5
20	MC-20R	100	10 ± 1	1 ± 0.4	26 ± 0.2	5 ± 0
21	MC-7 F***	100	83 ± 1	87 ± 0	92 ± 0.5	74 ± 0
22	MC-14 F***	100	99 ± 0	100 ± 0.4	91 ± 0.5	100 ± 0
23	MC-17 F	100	53 ± 1	28 ± 0	0 ± 0	7 ± 0
24	MC-21 F	100	0 ± 0	8 ± 0.3	11 ± 0.3	17 ± 0
25	MC-22 F***	100	84 ± 1	75 ± 0.3	88 ± 0.4	80 ± 0.2
26	MC-23 F	100	0 ± 0	9 ± 0.2	0 ± 0	33 ± 0.4
27	MC-25 F	100	45 ± 1	90 ± 0.2	77 ± 0	81 ± 0.6
28	MC-26 F	100	94 ± 0	87 ± 0.5	97 ± 0.5	91 ± 0.2
	Paclitaxel	1 μM	79 ± 1
	5-Fluorouracil	20 μM		45 ± 0
	Adriamycin	1 μM			46 ± 0.7
	Mitomycin	1 μM				63 ± 0

ISSN: 1471-2180