Methicillin resistance and virulence genes in invasive and nasal Staphylococcus epidermidis isolates from neonates

Table 3 Virulence genes profiles and SCCmec types identified among 50 Staphylococcus epidermidis isolates from bloodstream infection and nasal colonization

S. epidermidis isolates source (n)^a	Isolates	Biofilm-associated virulence genes ^c										SCCmec types (n) ^{b, d}
S. epidermidis isolates source (n)^a	(n)^b	icaADB	aae	aap	atlE	bhp	embp	fbe	gehD	sdrF	sesI	SCCmec types (n) ^{b, d}
BSI and Nasal (22)	6 (1B + 5 N)	+	+	+	+	-	+	+	+	-	-	V (1B + 2 N), nt1, nt3, nt7
	4 (1B + 3 N)	-	+	+	+	-	+	+	+	-	-	IV (1B), nt1, nt10, na
	3 (2B + 1 N)	-	+	+	+	-	+	+	-	-	-	IV (1B), nt3, na
	3 (1B + 2 N)	+	+	+	+	-	+	+	-	-	-	nt3 (1B), nt1 (2 N)
	2 (1B + 1 N)	-	+	-	+	-	+	+	+	-	-	IV (1B), nt3
	2 (1B + 1 N)	+	+	+	+	-	+	+	+	+	-	nt2 (1B), V
	2 (1B + 1 N)	-	+	+	+	-	+	-	-	-	-	nt2 (1B), nt4
BSI (23)	4	+	+	+	+	-	+	+	+	+	+	III, nt5, nt9, nt12
	3	-	+	+	+	-	+	+	+	+	+	IV (2), nt8
	2	-	+	+	+	-	+	+	+	+	-	IV, na
	1	+	+	-	+	-	+	+	+	+	+	III
	1	-	+	+	+	-	+	+	+	-	+	IV
	1	+	+	-	+	-	+	+	+	+	-	IV
	1	-	+	-	+	-	+	+	+	+	+	IV
	1	+	+	-	+	-	+	-	+	-	-	V
	1	-	+	-	+	-	+	-	-	+	+	nt2
	1	+	+	-	+	-	-	+	+	+	+	nt6
	1	+	+	-	+	-	-	+	-	-	-	nt13
	1	-	+	-	+	+	+	-	+	+	-	na
	1	-	+	-	+	-	+	-	+	-	-	nt1
	1	-	+	-	+	-	+	-	+	+	-	nt1
	1	+	+	+	+	-	+	+	-	+	-	nt11
	1	-	+	-	-	-	-	-	+	+	-	na
	1	+	+	-	+	-	+	-	-	+	-	nt14
Nasal (5)	2	-	+	-	+	-	+	+	-	-	-	nt1
	1	+	+	+	+	-	+	-	-	-	-	nt4
	1	+	+	+	+	-	+	-	+	-	-	nt1
	1	-	+	+	+	+	+	+	-	+	-	nt2

^a BSI: Bloodstream infection isolates
^b B: Bloodstream infection isolates; N: Nasal isolates
^c +: presence; -: absence
^d III: mec complex A/ccr 3; IV: mec complex B/ccr 2; V: mec complex C/ccr 5; nt: non-typeable; na: not-applicable (methicillin-sensitive isolate); nt1: mec complex -/ccr -; nt2: mec complex -/ccr 2; nt3: mec complex C/ccr -; nt4: mec complex -/ccr 5; nt5: mec complex A/ccr -; nt6: mec complex A/ccr 3,4 and 5; nt7: mec complex B/ccr -; nt8: mec complex B/ccr 2 and 4; nt9: mec complex B/ccr 4 and 5; nt10: mec complex C/ccr 2 and 5; nt11: mec complex C/ccr 4 and 5; nt12: mec complex C/ccr 2,4 and 5; nt13: mec complex -/ccr 4; nt14: mec complex -/ccr 4 and 5

ISSN: 1471-2180