Fig. 2

Relevant part of the Xanthomonas campestris pv. campestris sugar nucleotide metabolism producing precursors for the synthesis of the LPS O-antigen and the exopolysaccharide xanthan. Enzymatic reactions are indicated by arrows and names of the involved genes. Mutated genes of the strains Xcc H21012 (wxcB), Xcc H20110 (wxcN) and Xcc H28110 (wxcK) are indicated in bold red letters at their respective position within the metabolic pathway. Molecules are numbered as followss: 1: D-Glucose; 2: D-Glucose 6-phosphate; 3: D-Glucose 1-phosphate; 4: D-Mannose 1-phosphate; 5: GDP-D-mannose; 6: GDP-D-rhamnose; 7: dTDP-4-keto-6-deoxy-D-glucose; 8: dTDP-3-keto-6-deoxy-D-galactose; 9: dTDP-3-amino-3,6-dideoxy-D-galactose (dTDP-D-fucosamine); 10: dTDP-N-acetyl-fucosamine; 11: dTDP-4-keto-6-deoxy-L-mannose; 12: dTDP-L-rhamnose; 13: UDP-D-glucose; 14: UDP-D-glucuronic acid; 15: UDP-D-galacturonic acid; 16: OA repetitive subunit, dashed lines indicate uncertainties regarding the OA biosynthesis from rhamnose precursors. The xanthan precursors (5, 13, 14) are marked in green