Multilocus variable-number tandem repeat analysis for molecular typing and phylogenetic analysis of Shigella flexneri

Table 3 The discriminatory index (DI) and 95% confidence interval (CI) of various typing methods for serotype groups.

Typing method	Total (n = 242)			2a (n = 90)			4a/Y (n = 107)^c
	No. types	DI	CI	No. types	DI	CI	No. types	DI	CI
PFGE	95	0.908	0.8778-0.9385	44	0.9421	0.9100-0.9742	19	0.5733	0.4681-0.6785
MLVA4^b	82	0.9149	0.8879-0.9418	48	0.9745	0.9643-0.9847	14	0.6438	0.5503-0.7373
MLVA8^c	90	0.9163	0.8891-0.9434	51	0.9778	0.9682-0.9874	NA	NA	NA
MLVA36	104	0.927	0.9008-0.9539	54	0.9800	0.9708-0.9893	14	0.6438	0.5503-0.7373

^aIncluding an isolate with Y serotype, which was a single-locus variant of the predominant MLVA type of subserotype 4a.
^bFor the total: SF3, SF4, SF6, SF7; for 2a group: SF3, SF4, SF6, SF7; for 4a group: SF2, SF3, SF17, SF22
^cFor the total: SF3, SF4, SF6, SF7, SF8, SF9, SF10, SF25; 2a group: SF3, SF4, SF6, SF7, SF8, SF9, SF11, SF27

ISSN: 1471-2180