Figure 1From: Chlamydophila pneumoniae derived from inclusions late in the infectious cycle induce aponecrosis in human aortic endothelial cellsLytic capability of C. pneumoniae. HAEC were infected or additionally treated with chloramphenicol. LDH release was analyzed in three independent experiments 24 h, 48 h and 72 hpi and mean chlamydial induced specific lysis was calculated. Mean and SD (N = 3) at 48 hpi is shown. Significant differences are indicated if p < 0.05 as calculated by students t-test. C. pneumoniae specific lysis of HAEC is dose dependent and reaches a plateau at 20 IFU/cell. In contrast chloramphenicol treated infected HAEC were not lysed.Back to article page