The Vacuolar ATPase from Entamoeba histolytica: Molecular cloning of the gene encoding for the B subunit and subcellular localization of the protein

Table 1 Genes encoding for putative subunits of the vacuolar ATPase of Entamoeba histolytica

Subunit	Gene	Locus	Function^#
A (Q24802)*	Ehvma1	EHI_043010^¶	Catalytic site and regulation
B (Q4VSM4)*	Ehvma2	EHI_189850^¶	Non-catalytic site
	ψEhvma2	122.t00032^§	Involved in targeting?
C	Ehvma5	EHI_059840^¶	Assembly and activity
D	Ehvma8-1	EHI_056390^¶	Assembly and activity
	Ehvma8-2	202.t00016^§
E	Ehvma4-1	9.t00012^§	Assembly and activity
	Ehvma4-2	9.t00013^§
F	Ehvma7	EHI_007940^¶	Assembly and activity
G	Ehvma10	94.t00029^§	Assembly and activity
H	Ehvma13	215.t00004^§	Activity, but not assembly
a	Ehvph1	EHI_074020^¶ 417.t00001^§	H+ transport, assembly, and targeting
	Ehstv1	EHI_107280^¶
c (Q24810)*	Ehvma3	EHI_059840^¶	H+-transport; DCCD-binding site
c"	Ehvma16	289.t00003^§	H+ transport
d	Ehvma6	161.t00001^§	Activity and assembly

*UniProtKB/TrEMBL Accession number.
^¶Locus name assigned at Pathema (Bioinformatics Resource Center; http://pathema.jcvi.org/cgi-bin/Entamoeba/PathemaHomePage.cgi).
^§Locus with its provisional names in the E. histolytica genome project at The J. Craig Venter Institute.
^#Function was assigned based on reference [5].

ISSN: 1471-2180