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Table 3 Amino acid variability of Pre-S2 and S regions

From: Hepatitis B virus genotypes and resistance mutations in patients under long term lamivudine therapy: characterization of genotype G in Brazil

Pre-S2

S

Genotype/Isolate

07

14

18

30

31

32

33

35

37

41

42

46

48

49

51

54

08

18

20

44

45

49

51

63

68

195

G

A

N

K/T*

G

I/T

V

N/S

V

T

H

I

F

R/K

I

D

P

F

G

F

G

V/A

P

L

I

T

I

05-hgg

-

D

R

-

T

L

-

-

N

-

-

S

-

T

-

T

-

-

-

-

S

L

Q

T

I

M

06-hac

Q

-

-

E

T

Q

-

-

-

L

T

-

K

T

G

-

L

-

-

E

-

-

-

-

-

M

09-hgg

Q

-

-

E

T

A

E

A

-

L

T

-

K

T

G

-

L

V

C

E

-

-

-

-

-

M

F

Q

D

R

-/E

T

Q

-

A/-

-

L

T

-

K

T

G

T/M

L

V

C

-

T/L

-

Q

T

T

I

H

Q

D

R

E

T

Q

-

A

-

L

T

-

K

T

-

M

L

G

-

V

P

-

Q

T

T

I

D

T

D

R

-

T

-

-

-

-

-/P

-/L

-

-

-

-

-/L

-

G

-

-

T

L

Q

T

T

I

E

T

D

R

-

T

-

-

-

-

L

-

-

-

-

-

-

-

G

-

-

A

L

Q

T

I

I

B

T

D

R

-

T

-

-/S

A/-

N

A/S

-

-/L

K

T

-

-

L

G

-

-/E

T

L

Q

T

T/I

I

C

T

D

R

-

T

-

-

-

-

P/L

-

F

-

T/-

-

T/-

-

G

-

-

A

L/-

Q

T

I

I

A

-/N

D

R/K

-

T

-/L

-

A/-

-/N

-

-

S

-

T/-

-

T/-

-

G

-

-

A/S

L

Q

T

I

I

  1. -: same amino acid as genotype G consensus; *When two amino acids are separated by a slash, the first one represents the consensus of the genotype while the second one was only describewd in few isolates