Figure 4
From: Effect of gonococcal lipooligosaccharide variation on human monocytic cytokine profile
Comparison of TNFα production upon challenge with live gonococci vs. challenge with purified LOS. THP-1 cells (1 × 106/ml) were challenged with either 1 × 105/ml live gonococci or a molar equivalent amount of LOS/LPS (10 ng/ml). At three hours post challenge, sample supernatants were analyzed for TNFα by ELISA. These data represent two experiments, each performed in triplicate. Error bars indicate the standard deviation. (Rc LPS was purified from a rough LPS E. coli variant.)