Skip to main content

Table 2 Predicted DtxR-binding sites in C. diphtheriae

From: Prediction of DtxR regulon: Identification of binding sites and operons controlled by Diphtheria toxin repressor in Corynebacterium diphtheriae

Score

Position

Site

Gene

Synonym

Product

4.45904

-80

TGAGGGGAACCTAACCTAA

hmuO

DIP1669**

heme oxygenase

4.39003

-52

TTAGGATAGCTTTACCTAA

Tox

DIP0222**

Diphtheria toxin precursor

4.25877

-60

ATAGGCTACACTTACCTAA

-

DIP0624

Putative membrane protein

4.21068

-168

TTGGATTAGCCTACCCTAA

-

DIP2162**

ABC-type peptide transport system periplasmic component

4.2033

-21

TTAGGGTAGCTTCGCCTAA

iucA

DIP0586

Putative siderophore biosynthesis related protein

4.17632

-78

ATAGGCATGCCTAACCTCA

-

DIP2330

Putative membrane protein

4.07921

-130

TTAGGTCAGGGTACCCTAA

-

DIP0370

Putative succinate dehydrogenease cytochrome B subunit

4.03559

-30

TTAGCTTAACCTTGCCTAT

arsR

DIP0415

Putative ArsR family regulatory protein

4.01967

-239

TTAGGGTAGGCTAATCCAA

sidA*

DIP2161

nonribosomal peptide synthase

3.99985

-74

TTTTCTTTGCCTAGCCTAA

irp6A

DIP0108**

Ferrisiderophore receptor Irp6A

3.99195

-241

TTAGGCACCCCTAACCTAG

-

DIP0539

Putative sugar ABC transport syste ATP-binding protein

3.98554

-72

TTAGCTTAGCCCTAGCTAA

-

DIP0169

Putative secreted protein

3.9296

-26

CTAGGATTGCCTACACTTA

Irp5

DIP0894**

Conserved hypothetical protein

3.9073

-93

GTTGGGTTGCCCAACCTAC

-

DIP2106

Putative ABC transport system, ATP-binding subunit

3.89763

-86

ATAGGTTAGGTTAACCTTG

chtA*

DIP1520

Putative membrane protein

3.89676

-130

TTGTGTTAGCCTAGGCTAA

secA

DIP0699

Translocase protein

3.89169

-26

TTGGGGTGGCCTATCCTTA

-

DIP2304

Putative DNA-repair glycosylase

3.88042

-172

TTAGGTAAGTGTAGCCTAT

htaA*

DIP0625

Putative membrane protein

3.86534

-69

ATTACTAATGCTAACCTAA

Irp4

DIP2356**

Putative conserved membrane protein

3.85539

-173

TTAGGGTGGGCTAACCTGC

deoR*

DIP1296

Putative DNA-binding protein

3.84889

-75

TTAGGGAACTCTTGCCTTA

piuB*

DIP0124

Putative membrane protein

3.83816

-121

TTAGCTAGGGCTAAGCTAA

-

DIP0168

Putative glycosyl transferase

3.83576

-219

GTAACAAAGGCAAGCCTAA

xerD

DIP1510

Putative integrase/recombinase

3.8224

-216

ATAGGCAAGGTTAAGCTAA

-

DIP0417

Putative membrane protein

3.81905

-47

GTTGGACAGGTTACCCTAA

frgA*

DIP1061

Putative iron-siderophore uptake system permease

3.8148

-37

TGTGGGCACACCAACCTAA

-

DIP2272

possible sortase-like protein

3.76235

-136

TTGGGGTTGCCCTTCCTAA

-

DIP0142

Hypothetical protein

3.76233

-268

CTAGGTTAGGGGTGCCTAA

secY*

DIP0540

preprotein translocase SecY subunit

3.74673

-110

TAAACATAGCCAAACCAAA

nrdF1

DIP1865

ribonucleotide reductase beta-chain 1

3.7438

-81

TAAGGATAGGCCACCCCAA

Dps

DIP2303

Starvation inducible DNA-binding protein

  1. Note: **Indicate the gene synonym with experimentally identified binding site in C. diphtheriae [6]. * Indicates the genes known to be regulated by DtxR [7]. The binding sites in Italics were verified by EMSA. The gene pairs, DIP0624-DIP0625, DIP2161-DIP2162, DIP0168-DIP0169, DIP0539-DIP0540 and DIP2303-DIP2304 are divergently transcribed and contain common regulatory regions.