Effects of natural and chemically synthesized furanones on quorum sensing in Chromobacterium violaceum

BMC Microbiology

Table 1 Effects of the compounds listed in Figure 1 on quorum sensing and growth.

Compound	Activation no HHL Comp. 10^-4 M	Toxic no HHL Comp. 10^-2 M	Inhibition 1 HHL 3.7*10^-8 M Comp. 10^-4 M	Inhibition 2 HHL 10^-6 M Comp. 10^-4 M	Enhanced Expression HHL 4.6*10^-9 Comp. 10^-5 M
	1	2	3	4	5
1.01	-0.04	0.65	0.78	0.77	1.74
3.01	0.02	1.26	0.29	0.70	0.74
3.02	0.03	1.29	0.65	0.33	1.42
3.11	0.00	0.97	0.31	0.18	0.18
3.12	-0.01	0.96	0.69	0.45	1.21
3.21	-0.02	0.83	0.83	0.95	2.41
3.22	-0.02	0.75	0.73	0.54	1.27
3.31	-0.05	0.50	0.20	0.36	0.82
3.32	-0.08	0.38	0.51	0.28	1.05
3.41	-0.02	0.80	0.60	0.90	1.07
3.51	-0.06	0.52	0.87	0.94	1.15
4.01	0.00	1.03	0.32	0.47	1.22
4.02	0.00	0.97	0.40	0.24	0.23
4.11	-0.01	0.86	0.58	0.67	0.94
4.12	-0.05	0.65	0.36	0.36	0.52
4.21	-0.03	0.76	0.66	0.51	1.37
4.22	-0.03	0.72	0.74	0.52	1.64
4.31	-0.06	0.49	0.44	0.32	0.86
4.32	-0.04	0.53	0.47	0.51	0.90
4.51	0.03	1.17	0.70	0.98	0.97
11	0.02	1.19	0.96	0.97	2.17
12	0.11	1.79	0.42	0.62	2.66
13	-0.04	0.53	0.84	0.62	1.81
14	0.00	1.03	0.92	0.91	1.69
15	-0.03	0.68	0.46	0.25	0.96
16	0.01	1.10	0.84	0.84	1.46
17	0.00	1.04	0.95	0.97	0.81
18	-0.09	0.60	0.93	0.57	0.91
19	-0.06	0.55	0.74	0.78	1.02
20	0.01	1.12	0.92	0.84	1.63
21	-0.02	0.83	0.57	0.41	1.31
22	-0.04	0.59	0.32	0.39	0.96
DHL	0.78	3.76	0.78	0.58	2.71

Column 1: activation of QS = bold. Growth control = 0, 3.7*10^-8M HHL = 1. Column 2: growth stimulation (> 1.15) = bold, growth inhibition (< 0.6) = italics, growth control = 1. Column 3: inhibition of QS induced by 3.7*10^-8M HHL (< 0.60) = italics, control = 1. Column 4: inhibition of QS induced by 10^-6 M HHL, > 0.15 less inhibitory than column 3 = bold, > 0.15 more inhibitory than column 3 = italics, control = 1. Column 5: synergistic effect to HHL = bold, control = 1.

ISSN: 1471-2180