Figure 5From: HIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell-cycle mechanisms contributing to the proliferative phenotype in HIV-associated nephropathyMapping of HIV-1 genes that induce cyclin D 1 expression. Northern blot detection of cyclin D1 and G3PDH transcripts from wild-type, control-infected, and HIV-1-infected podocytes infected with single gene mutants of HIV-1 (tat present in every virus). Similar to wild-type and control-infected podocytes, podocytes infected with nef-deficient HIV-1 do not significantly up-regulated cyclin D1 expression compared to podocytes infected with other single gene mutant viruses.Back to article page