Figure 4From: RpoS integrates CRP, Fis, and PhoP signaling pathways to control Salmonella Typhi hlyE expression Model showing that CRP, Fis and PhoPQ regulate taiA-hlyE operon expression via RpoS. RpoS integrates multiple environmental signals through different global regulators in order to regulate the taiA-hlyE operon expression. Like hlyE, taiA expression is up-regulated by RpoS and PhoPQ under low pH and low Mg2+ concentrations [11, 14].Back to article page