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Table 3 Antibiotic resistance gene profiles of the 21 E. faecium strains

From: Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes

Gene

cat

ermA

ermB

aad6

aad9

aadE

aacA- aphD

tetL

tetM

vanA

gyrA b

parC c

pbp5-Rd

Resistance

CHL

ERY

ERY

SPC/ STR

SPC/ STR

SPC/ STR

GEN

TET

TET

VAN

CIP

CIP

AMP

Strains

             

1,141,733

             

Com12

             

Com15

             

E980

             

TX1330

             

1,230,933

  

X

X

 

X

X

 

X

X

X

X

X

1,231,408

  

X

X

 

X

X

   

X

X

X

1,231,410

  

X

X

 

X

   

X

X

 

X

1,231,501

             

1,231,502

  

X

X

 

X

X

  

X

X

X

X

C68

  

X

X

 

X

X

 

X

 

X

X

X

D344SRFa

  

X

X

 

X

 

X

X

    

TX16

X

 

X

X

 

X

 

X

X

   

X

E1039

            

X

E1071

X

 

X

X

X

X

 

X

 

X

  

X

E1162

       

X

X

   

X

E1636

        

X

   

X

E1679

 

X

X

X

X

 

X

  

X

X

X

X

TX82

  

X

X

 

X

  

X

X

X

X

X

TX0133A

X

 

X

X

 

X

X

 

X

 

X

X

X

U0317

  

X

X

 

X

X

   

X

X

X

  1. aA rifampin- and fusidic acid-resistant derivative of clinical strain E. faecium D344S in which the spontaneous loss of pbp5 and its surrounding region resulted in an ampicillin-susceptible phenotype.
  2. bAmino acid change (E to K/G) in residue 87 or (S to R/Y/I) in residue 83 of GyrA.
  3. cAmino acid change (E to K) in residue 86 or (S to R/I) in residue 82 of ParC.
  4. dConsensus sequence of the pbp5-R allele encoding the low affinity Pbp5-R.
  5. eTC6 was not included in this analysis as it is a transconjugant of C68 and D344SRF, so therefore is not a unique genome.