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Table 1 List of M. tuberculosi s H37Rv and M. tuberculosi s H37Ra proteins, with difference in relative abundance of 5 fold or higher.

From: Comparison of membrane proteins of Mycobacterium tuberculosisH37Rv and H37Ra strains

Protein IDs

Protein description

Gene Name

Functional group

Ratio H37Rv/H37Ra

Ratio H37Ra/H37Rv

TM number

References

Rv0319

Probable conserved integral membrane protein

-

3

-

6 b

8 c

 

Rv1101c

Conserved membrane protein

-

3

-

5

8

[21, 60]

Rv1030

Probable potassium-transporting p-type

-

3

-

12

7

 

Rv2560

Probable proline and glycine rich transmembrane

-

3

-

24

4

[21]

Rv2732c

Probable conserved transmembrane protein

-

3

-

7

4

 

Rv0014c

Transmembrane serine/threonine-protein kinase b

-

9

-

18

1

[21]

Rv3584

Possible conserved lipoprotein

lpqe

3

-

11

1

[21, 60–63]

Rv3869

Possible conserved membrane protein

-

3

-

6

1

 

Rv0070c

Probable serine hydroxymethyltransferase

glya2

7

-

82

0

[64]

Rv3576

Possible conserved lipoprotein

lpph

3

-

11

0

[21]

Rv0402c

Probable conserved transmembrane transport

-

3

7a

-

12

[61, 64]

Rv0933

Phosphate-transport ATP-binding ABC transporter

pstB

3

106

-

0

 

Rv3273

Probable transmembrane carbonic anhydrase

-

7

33

-

10

[60, 62, 63]

Rv2051c

Polyprenol-monophosphomannose synthase

ppm1

3

22

-

7

[63, 64]

Rv2877c

Probable conserved integral membrane protein

-

3

5

-

7

 

Rv1273c

Probable drugs-transport transmembrane

-

3

7

-

6

 

Rv1819c

Probable drugs-transport transmembrane

-

3

6

-

6

[60, 63, 64]

Rv2586c

Probable protein-export membrane protein

secf

3

7

-

6

[21, 60, 63]

Rv1779c

Hypothetical integral membrane protein

-

3

21

-

4

[64]

Rv2197c

Probable conserved transmembrane protein

-

3

8

-

4

[21, 63]

Rv2617c

Probable transmembrane protein

-

3

11

-

3

 

Rv0284

Possible conserved membrane protein

-

3

11

-

1

[60, 63, 64]

Rv0291

Probable membrane-anchored mycosin

mycp3

7

6

-

1

[60–63]

Rv1209

Conserved hypothetical protein

-

10

19

-

1

[21, 63]

Rv1885c

Conserved hypothetical protein

-

10

7

-

1

[21]

Rv2289

Probable cdp-diacylglycerol pyrophosphatase

cdh

1

42

-

1

[21, 60, 63]

Rv0265c

Probable periplasmic iron-transport lipoprotein

-

3

7

-

0

[21, 61–63]

Rv0583c

Probable conserved lipoprotein lpqn

lpqn

3

19

-

0

[21, 60, 61, 63]

Rv2833c

Probable sn-glycerol-3-phosphate-binding

-

3

9

-

0

[21, 64]

  1. a Proteins more abundant in M. tuberculosis H37Rv strain compared to H37Ra strain. Relative abundance ratio calculated based on intensity measurements performed using MSQuant algorithm http://msquant.sourceforge.net/.
  2. b Proteins more abundant in M. tuberculosis H37Ra strain compared to H37Rv strain. Relative abundance ratio calculated based on intensity measurements performed using MSQuant algorithm http://msquant.sourceforge.net/.
  3. c Number of transmembrane regions predicted in the primary amino acid sequence by TMHMM v 2.0 http://www.cbs.dtu.dk/services/TMHMM/.
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BMC Microbiology

ISSN: 1471-2180

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