Figure 4
From: Rhomboid homologs in mycobacteria: insights from phylogeny and genomic analysis
Mycobacterial rhomboids are active rhomboid proteases. Highlighted in blue are the rhomboid catalytic dyad residues (Ser201 and His254); yellow, the invariant residues in this alignment; grey, the rhomboid family invariant residues that were not conserved in this alignment. Locus tags for mycobaterial rhomboids are boxed blue. Included: aarA [GenBank: L28755] of P. stuartii; glpG [GenBank: AAA23890] of E. coli; rho-1 [GenBank: AAF47496.1] of Drosophila; (Ano1) AgaP_AGAP004737 [GenBank: XP_318085] of Anopheles gambiensi; (Tox1) [GenBank: #Q695U0] of Toxoplasma gondii; (Fal1) PF11_0149 [GenBank: XP_001347820] of P. falciparum and RHBDL2 [GenBank: NP_060291.2] of human.