Table 1 Functional classification of the identified M. tuberculosis H37Rv proteins.
Functional group a | Functional group no. | Total protein number b | Number of observed proteins c |
|---|---|---|---|
Virulence, detoxification, adaptation | 0 | 212 | 44 (21%) |
Lipid metabolism | 1 | 237 | 84 (35%) |
Information pathways | 2 | 232 | 98 (42%) |
Cell wall and cell processes | 3 | 751 | 313 (42%) |
Stable RNAs | 4 | 50 | 0 (0%) |
Insertion sequences and phages | 5 | 147 | 0 (0%) |
PE/PPE | 6 | 168 | 14 (8%) |
Intermediary metabolism and respiration | 7 | 898 | 412 (46%) |
Unknown | 8 | 15 | 0 (0%) |
Regulatory proteins | 9 | 194 | 54 (28%) |
Conserved hypotheticals | 10 | 895 | 299 (33%) |
Conserved hypotheticals with an orthologue in M. bovis | 16 | 262 | 52 (20%) |