Fig. 5
EPS clusters analysis, serum bactericidal assay, and neutrophil phagocytotic assay. A) Genomic organization of the EPS gene cluster in L. paracasei LP10266, L. casei LC2W, L. casei LOCK919, L. paracasei N1115, L. paracasei TK1501, and L. paracasei TMW1.1434. The genes common in all genomes are shown in gray, and the genes exclusively identfied in L. paracasei LP10266 are shown in red; 10 kb is the unit length of a gene cluster; the arrow length is proportional to the length of the gene; and the arrow direction represents the transcription direction of the gene. B) Serum bactericidal assay of L. paracasei LP10266 and L. paracasei ATCC25302. A slight decrease was observed in the growth of L. paracasei LP10266. Data are presented as mean ± standard error of mean. C) Microscopic observations under an oil immersion lens of neutrophil phagocytosis of L. paracasei ATCC25302 and L. paracasei LP10266. D) The correlation between repeated measurements revealed by the test of sphericity (p < 0.01). Statistically significant differences were observed at different time points in the overall mean of the data (p < 0.01), and interaction was observed between the grouping factors and the repeated measurement factors. The test of Between-Subjects Effects revealed a significant difference of neutrophil phagocytosis between L. paracasei strains LP10266 and ATCC25302 (p = 0.044)