Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds

Table 2 List of the 20 most differentially down regulated genes of the shared genome of the three E. coli strains in lamb’s lettuce medium vs. M9 minimal medium containing 0.4% (w/v) glucose

		log₂FC
Gene symbol	Gene description^a	O157:H⁻ str. 3072/96	O104:H4 str. C227–11ϕcu	O157:H7 str. Sakai
zinT	metal-binding protein ZinT	−8.15	−5.86	−8.25
trpE	anthranilate synthase subunit TrpE	−6.41	−5.64	−8.41
hycA	regulator of the transcriptional regulator FhlA	−7.72	−7.13	−4.89
ykgM	putative ribosomal protein	−7.30	−3.46	−7.39
thiE	thiamine phosphate synthase	−5.31	−7.18	−4.75
thiF	ThiS adenylyltransferase	−5.51	−6.84	−4.78
gadB	glutamate decarboxylase B	−5.39	−5.18	−6.47
thiC	phosphomethylpyrimidine synthase	−5.41	−6.44	−4.80
thiH	2-iminoacetate synthase	−5.01	−6.66	−4.80
mtr	tryptophan:H(+) symporter Mtr tryptophan transporter of high affinity	−5.25	−4.98	−6.11
gadA	glutamate decarboxylase A	−5.04	−5.77	− 5.32
thiG	1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase	−4.90	−6.43	−4.64
trpD	anthranilate synthase subunit TrpD	−5.28	−3.62	−6.84
gadC	L-glutamate:4-aminobutyrate antiporter	−5.11	−4.07	−6.38
yegX	putative hydrolase	−3.75	−6.42	−3.80
nadB	L-aspartate oxidase	−4.34	− 4.54	−4.90
yhiM	inner membrane protein with a role in acid resistance	−4.80	−2.92	−5.92
thiD	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	−3.74	−5.56	−4.09
alaE	L-alanine exporter	−3.99	−5.73	−3.33
grcA	stress-induced alternate pyruvate formate-lyase subunit	−4.54	− 4.86	−3.29

ISSN: 1471-2180