Table 1 Patient demographics (n = 40)
Total n: 40 | GNB recolonization n: 28 | GNB de-novo colonization n: 7 | Exempt of GNB n: 5 | p | |
|---|---|---|---|---|---|
Age, years | 28.5 ± 10.46 | 28.6 ± 9.2 | 25.4 ± 8.9 | 34.2 ± 15 | 0.33 |
Sex, male | 19 (47.5%) | 14 (50%) | 4 (57%) | 1 (20%) | 0.40 |
High emergency LTx | 7 (17.5%) | 6 (21.4%) | 0 | 1 (20%) | 0.40 |
Bilateral LTx | 39 (97.5%) | 28 (100%) | 6 (85.7%) | 5 (100%) | 0.09 |
HLTx | 1 (2.5%) | 0 | 0 | 0 | 0.09 |
Lung ischemic time, minutes | 355 ± 86.1 | 360 ± 99.5 | 351 ± 41.1 | 330 ± 33.2 | 0.77 |
CMV D+/R- | 4 (10%) | 2 (7.1%) | 1 (14.3%) | 1 (20%) | 0.62 |
ICU length of stay, days | 25.2 ± 33.2 | 30.8 ± 38 | 8.4 ± 5.2 | 17.2 ± 12 | 0.24 |
Length of invasive mechanical ventilation, days | 17.5 ± 32.4 | 21.9 ± 38.3 | 3.7 ± 3.3 | 6.2 ± 5.5 | 0.36 |
Follow up, days | 1413.5 ± 565.8 | 1509.3 ± 527.8 | 1044.3 ± 590.7 | 1394.2 ± 643.2 | 0.15 |
One year survival, % | 100 | 100 | 100 | 100 | |
Best post-transplant FEV1, %predicted | 83.8 ± 18 | 82.5 ± 19.3 | 90.8 ± 12.6 | 82.2 ± 16.7 | 0.59 |
CLAD | 9 (22.5%) | 3 (10.7%) | 4 (57%)* | 2 (40%) | 0.02* |
BOS | 7 (17.5%) | 3 (10.7%) | 2 (28.6%) | 2 (40%) | 0.20 |
Time to BOS, months | 36.4 (20.2) | 27.3 (18.5) | 25.5 (6.4) | 61 (5.7) | 0.09 |
RAS | 2 (5%) | 0 | 2 (28.6%)* | 0 | 0.007* |
Time to RAS, months | 13 | NA | 13 | NA |