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Table 2 Exploring the presence of LuxS, Pfs, LuxP, LsrB, RbsB and SAH hydrolase in thermophilic eubacteria by using the protein sequences of LuxS, Pfs, LsrB of E. coli str. K-12 substr. MG1655, LuxP of V. harveyi, RbsB of A. actinomycetemcomitans SAH hydrolase of Ralstonia solanacearum as queries

From: Quorum sensing in thermophiles: prevalence of autoinducer-2 system

Phylum

Bacteria

LuxS

Pfs

LuxP

LsrB

RbsB

SAH hydrolase

Possible role

 

Identity (%)

Aquificae

Desulfurobacterium thermolithotrophum

43

Metabolism (Detoxification of SAH)

Desulfurobacterium atlanticum

Could not be determined

Desulfurobacterium pacificum

Could not be determined

Sulfurihydrogenibium yellowstonense

43

Metabolism (Detoxification of SAH)

Sulfurihydrogenibium azorense

42

Metabolism (Detoxification of SAH)

Sulfurihydrogenibium subterraneum

42

Metabolism (Detoxification of SAH)

Thermovibrio ammonificans

42

Metabolism (Detoxification of SAH)

Thermovibrio ruber

Could not be determined (Unknown)

Bacteroides

Anaerophaga thermohalophila

24

63

D-ribose transporter and metabolism (Detoxification of SAH)

Chloroflexi

Chloroflexus aurantiacus

Could not be determined

Chloroflexus aggregans

52

43

D-ribose transporter and metabolism (Detoxification of SAH)

Thermomicrobium roseum

43

Metabolism (Detoxification of SAH)

Deferribacteres

Deferribacter thermophilus

Could not be determined

Deferribacter desulfuricans

40

Metabolism (Detoxification of SAH)

Deferribacter autotrophicus

Could not be determined

Deinococcus-Thermus

Marinithermus hydrothermalis

42

42

AI-2 synthesis and metabolism (Detoxification of SAH)

Meiothermus ruber

42

29

31

AI-2 synthesis

Meiothermus silvanus

43

36

39

33

43

AI-2 synthesis and metabolism

Meiothermus chliarophilus

44

33

32

41

AI-2 synthesis and metabolism

Meiothermus taiwanesis

42

AI-2 synthesis

Meiothermus cerbereus

41

AI-2 synthesis

Meiothermus rufus

39

AI-2 synthesis

Oceanithermus profundus

42

62

39

AI-2 synthesis

Thermus filiformis

42

31

AI-2 synthesis

Thermus parvatiensis

40

32

AI-2 synthesis

Thermus caliditerrae

40

34

AI-2 synthesis

Thermus oshimai

42

31

AI-2 synthesis

Thermus igniterrae

41

33

AI-2 synthesis

Thermus scotoductus

41

32

AI-2 synthesis

Thermus thermophilus

39

32

AI-2 synthesis

Thermus amyloliquefaciens

40

35

AI-2 synthesis

Thermus islandicus

40

34

49

AI-2 synthesis

Thermus aquaticus

40

AI-2 synthesis

Dictyoglomi

Dictyoglomus thermophilum

36

Metabolism (Detoxification of SAH)

Firmicutes

Ammonifex thiophilus

Could not be determined

Ammonifex degensii

36

Metabolism (Detoxification of SAH)

Anoxybacillus geothermalis

39

55

30

58

AI-2 synthesis

Anoxybacillus thermarum

36

56

AI-2 synthesis

Anoxybacilllus amylolyticus

39

56

59

AI-2 synthesis

Anoxybacillus suryakundensis

36

55

AI-2 synthesis

Anoxybacillus flavithermus

37

56

59

AI-2 synthesis

Caldanaerobacter subterraneus

25

59

Sugar ABC transporter

Caldanaerobacter uzonensis

Could not be determined

Caldicellulosiruptor saccharolyticus

39

Metabolism (Detoxification of SAH)

Caldicellulosiruptor kronotskyensis

39

Metabolism (Detoxification of SAH)

Caldicellulosiruptor bescii

38

Metabolism (Detoxification of SAH)

Carboxydothermus hydrogenoformans

39

Metabolism (Detoxification of SAH)

Carboxydothermus ferrireducens

39

Metabolism (Detoxification of SAH)

Coprothermobacter proteolyticus

61

37

D-ribose transporter and Metabolism (Detoxification of SAH)

Coprothermobacter platensis

39

Metabolism (Detoxification of SAH)

Geobacillus caldoxylosilyticus

40

54

AI-2 synthesis

Geobacillus stearothermophilus

39

53

58

AI-2 synthesis

Geobacillus thermoglucosidasius

38

53

57

AI-2 synthesis

Geobacillus kaustophilus

39

55

58

AI-2 synthesis

Geobacillus subterraneus

38

54

AI-2 synthesis

Geobacillus icigianus

39

55

57

AI-2 synthesis

Geobacillus thermoleovorans

39

55

58

AI-2 synthesis

Geobacillus thermonitrificans

38

55

57

AI-2 synthesis

Halothermothrix orenii

37

Metabolism (Detoxification of SAH)

Moorella thermoacetica

29

29

36

Sugar ABC transporter and Metabolism (Detoxification of SAH)

Natranaerobius thermophilus

59

39

D-ribose transporter and Metabolism (Detoxification of SAH)

Pelotomaculum thermopropionicum

39

Metabolism (Detoxification of SAH)

Thermosediminibacter oceani

39

37

29

AI-2 synthesis

Thermoanaerobacter kivui

40

43

62

AI-2 synthesis

Thermoanaerobacter thermocopriae

42

41

61

AI-2 synthesis

Thermoanaerobacterium thermosaccharolyticum

42

43

55

AI-2 synthesis

Thermoanaerobacterium saccharolyticum

43

47

AI-2 synthesis

Thermoanaerobacterium aotearoense

43

46

AI-2 synthesis

Thermoanaerobacterium xylanolyticum

43

46

AI-2 synthesis

Thermosinus carboxydivorans

38

Metabolism (Detoxification of SAH)

Nitrospirae

Thermodesulfovibrio aggregans

41

Metabolism (Detoxification of SAH)

Thermodesulfovibrio thiophilus

41

Metabolism (Detoxification of SAH)

Thermodesulfovibrio hydrogeniphilus

Could not be determined

Proteobacteria

Caminibacter mediatlanticus

55

36

AI-2 synthesis

Caminibacter profundus

Could not be determined

Caminibacter hydrogeniphilus

Could not be determined

Desulfacinum hydrothermale

Could not be determined

Desulfacinum infernurn

Could not be determined

Hippea maritime

42

Metabolism (Detoxification of SAH)

Hippea jasoniae

41

Metabolism (Detoxification of SAH)

Hippea alviniae

42

Metabolism (Detoxification of SAH)

Nitratiruptor SB155-S

66

34

AI-2 synthesis

Thermochromatium tepidum

Could not be determined

Thermodesulfobacteria

Fervidobacterium islandicum

27

51

37

D-ribose transporter and metabolism

Fervidobacterium gondwanense

Could not be determined

Fervidobacterium changbaicum

Could not be determined

Fervidobacterium nodosum

27

37

Metabolism (Detoxification of SAH)

Kosmotoga pacifica

53

D-ribose transporter

Kosmotoga olearia

53

D-ribose transporter

Kosmotoga arenicorallina

49

D-ribose transporter

Marinitoga piezophila

36

Metabolism (Detoxification of SAH)

Marinitoga camini

Could not be determined

Marinitoga hydrogenitolerans

Could not be determined

Petrotoga mobilis

53

36

D-ribose transporter and metabolism (Detoxification of SAH)

Petrotoga mexicana

Could not be determined

Petrotoga halophila

Could not be determined

Thermococcoides sp.

Could not be determined

Thermodesulfatator indicus

40

Metabolism (Detoxification of SAH)

Thermodesulfatator atlanticus

41

Metabolism (Detoxification of SAH)

Thermodesulfatator autotrophicus

40

Metabolism (Detoxification of SAH)

Thermosipho africanus

50

38

D-ribose transporter and metabolism (Detoxification of SAH)

Thermosipho melanesiensis

28

38

Metabolism (Detoxification of SAH)

Thermotoga petrophila

32

49

D-ribose transporter and metabolism

Thermotoga maritime

31

26

37

D-ribose transporter and metabolism (Detoxification of SAH)

Thermotoga neopolitana

30

36

38

D-ribose transporter and metabolism (Detoxification of SAH)

Thermotoga naphthophila

32

33

48

38

Sugar ABC transporter and metabolism (Detoxification of SAH)

  1. Protein sequences with the names LuxS, S-ribosylhomocysteine lyase, S-ribosylhomocysteinase, MTA/SAH nucleosidase, Pfs, Autoinducer-2 binding protein, RbsB and D-ribose transporter were only considered for analysis
  2. ‘-‘indicates not present or less than 25% identical, however some sequences are mentioned in the table having very less identity (< 24%), as they are showing the similar names in NCBI database as the proteins of autoinducer-2 pathway
  3. M. ruber, M. silvanus, M. chilarophilus, O. profundus, T. islandicus, A. geothermalis, A. amylolyticus, A. flavithermus, G. stearothermophilus, G. thermoglucosidasius, G. kaustophilus, G. icigianus, G. thermoleovorans, G. thermonitrificans, T. oceani, T. kivui, T. thermocopriae, T. thermosaccharalyticum have been found to have complete autoinducer-2 quorum sensing genes
  4. M. hydrothermalis, M. taiwanesis, M.cerbereus, M. rufus and T. aquaticus have only LuxS protein and no other autoinducer-2 quorum sensing protein
  5. T. oshimai, T. filiformis, T. parvatiensis, T. calditerrae, T. igniterrae, T. scotoductus, T. thermophilus, T. amyloliquefaciens, T. islandicus and Anoxybacillus thermarum, A. suryakundensis, G. caldoxylosilyticus, T. saccharolyticum, T. aotearoense, T. xylanolyticum, C. mediatlanticus and Nitratiruptor sp.possess both LuxS and Pfs protein and no other protein
  6. A. thermohalophila, C. aggregans, C. proteolyticus, N. thermophilus, K. pacifica, K. olearia, K. arenicorallina, P. mobilis, T. africanus, T. petrophila, T. maritima and T. neopolitana have only RbsB protein while C. subterraneus, M. thermoacetica and T. naphthophila have both LsrB and RbsB protein but no LuxS
  7. Phylum Aquificae, Deferribacteres, Dictyoglomi, Nitrospirae have none of the quorum sensing protein